Medical Information on Neurodevelopmental Disorders (M.I.N.D.)
"Medical Information on Neurodevelopmental Disorders"
was created in order to provide to physicians, and other interested parties, information regarding medical problems which are known to occur frequently in adults with severe "medically-complex" developmental disabilities. The site is produced and maintained by the medical staff of the Hunterdon Developmental Center, in Clinton NJ

The Concepts of "Neurodevelopmental Disorder" vs. "Developmental Disability"
It is important to distinquish the concept of developmental disability from that of neurodevelopmental disorder.
"Developmental disability" refers to "childhood-onset" (i.e. before the age of 22 years in NJ) "disabilty" ( i.e. persistant/permanent substantial functional limitation) secondary to dysfunction/disease of the central nervous system. This disability is often associated with mental retardation, seizures, cerebral palsy, or abnormal behaviors, either singly or in combination. The person with a developmental disability, because of the persistant substantial functional limitation, becomes eligible for a variety of government services which provide education, vocational support, recreational programs, and residential opportunities. Forty years ago these services were centralized in large state run facilities; however, today most people with developmental disabilities receive them from various community-based provider agencies. On the other hand there has been difficulty "mainstreaming" medical services as effectively as has been the case with the other services. Difficulty mainstreaming medical care appears to be in part related to the fact that physicians are not well-trained or experienced when it comes to the health conditions frequently encountered in adults with severe developmental disabilities (see below). It also appears to be related to the fact that, for the most part, physicians play only a small role in designing service policy, since policy tends to emphasize educational, vocational, recreational and residential services and supports, rather than medical concerns. This "social" paradigm is certainly appropriate for those individuals who have milder forms of developmental disabilities. Unfortunately, individuals with developmental disabilities who are medically fragile or complex and who therefore require a greater emphasis on medical services, often find that community-based medical professionals lack critical experience regarding their specific health needs. Some states (e.g. NJ and California) have recently undertaken initiatives designed to correct this problem. These initiatives include the creation of collaborations between Medical Schools (where research is generated and physician training occurs) with Human Services agencies (where responsibility for service resides).

"Neurodevelopmental disorder" refers to the specific medical disease or condition that causes the developmental disability in the first place (e.g. Down Syndrome, PKU, William's Syndrome, Perinatal hypoxia/ischemia). Neurodevelopmental disorders can be either "genetic" or "acquired"(see below). It is important for the physician to establish the precise etiology/syndrome of the neurodevelopmental disorder because knowing the exact cause then directs the physician towards syndrome-associated conditions that will need to be evaluated and monitored (e.g. thyroid dysfunction in Down Syndrome). Regardless of the exact cause, most people with neurodevelopmental disorders will have one or more of four "general" complications, namely: cognitive disability, neuromotor dysfunction, seizures, or abnormal behaviors. The purpose of this site is education regarding neurodevelopmental disorders, their precise diagnosis, and management of their complications. The issue of "disability" (i.e. the functional limitation) that results from the neurodevelopmental disorder, its social ramifications and its multidisciplinary management, while not being the primary focus of this site should nonetheless always be considered by the health care professional who is charged with the responsibility of providing services to an individual with a neurodevelopmental disorder.



A classification of neurodevelopmental disorders (click here )
Evaluation and Management of the Frequently Occuring Medical Conditions (
click here )
Developmental Medicine Reviews & Reports: Special Topics (
click here )