SIDNEY PESTKA |
Professor, Department
Chair, Molecular Genetics, Microbiology and Immunology, UMDNJ; M.D.,
University of Pennsylvania.Receptors, signal transduction, interferons
and cytokines; protein expression, structure and function; gene
therapy. Cell 76:793-802, 1994. |
JOSEPH P. DOUGHERTY |
Professor, Director of the Graduate
Program of Molecular Genetics, Microbiology and Immunology, UMDNJ;
Ph.D., Yale. Towards the development of a virus/cell based assay
for the discovery of novel compounds against HIV-1. Antimicrobial
Agents and Chemotherapy 47: 501-508 (2003). |
NANCY A. WOYCHIK |
Associate Professor
of Molecular Genetics, Microbiology and Immunology, UMDNJ, Ph.D.,
Wisconsin. Regulation of mRNA transcription by RNA polymerase II and
general transcription factors; RNA polymerase II subunit function.
Genes Dev. 9:481-490, 1995. |
CORY ABATE-SHEN |
Associate Professor of Neuroscience,
UMDNJ, and Resident Member of the Center for Advanced Biotechnology
and Medicine; Ph.D., Cornell. Transcriptional repression by Msx-1
does not require homeodomain DNA binding sites. Mol. Cell Biol.,
15:861-871. |
EDWARD ARNOLD |
Professor of Chemistry
and Chemical Biology, Rutgers University, and Resident Member, Center
for Advanced Biotechnology and Medicine; Ph.D., Cornell. Crystallographic
studies of human viruses and viral proteins. Molecular design including
drugs and vaccines. Polymerase structure. J. Mol. Biol. 264:1085-1100,
1996. |
GAIL FERSTANDIG ARNOLD |
Research Professor, Department of
Chemistry and Chemical Biology Rutgers University, Ph.D. Purdue
University, B.A. Cornell. Development of chimeric human rhinoviruses
as vaccines, immunotherapeutics, and diagnostic reagents; and understanding
of the sequence and structural basis of immunogenicity. J. Virol.
69:2406-2411, 1995. |
KENNETH J. BRESLAUER |
Professor of Chemistry
and Chemical Biology, Rutgers University, Ph.D., Yale.Communication
between noncontacting macromolecules. Annu. Rev. Biophys. Biomol.
Struct. 34:21-42 (2005).Conformational screening of oligonucleotides
by variable-temperature HPLC: Dissecting the duplex-hairpin-coil
equilibria of d(CGCGAATTCGCG). Biopolymers 74:221-231 (2004).The
thermodynamics of template-directed DNA synthesis: base insertion
and extension enthalpies. Proc. Natl. Acad. Sci. USA 100:14719-14724
(2003). |
GARY BREWER |
Professor of Molecular Genetics,
Microbiology and Immunology, UMDNJ; Ph.D., Vanderbilt University.Targeted
knockdown of the RNA-binding protein CRD-BP promotes cell proliferation
via an IGF-II-dependent pathway in human K562 leukemia cells. J.
Biol. Chem., 279:48716-48724. 2004. |
PATRIZIA CASACCIA-BONNEFIL |
Associate Professor
of Neuroscience and Cell Biology, UMDNJ; M.D., Ph.D., Catholic University,
Rome, Italy; SUNY HSCB.Adult neural stem cells; sex-dependent differences
in brain development and in susceptibility to diseases; pathogenesis
of neurological disorders, with a special emphasis on multiple sclerosis.
Lack of the cell-cycle inhibitor p27Kip1 results in selective increase
of transit-amplifying cells for adult neurogenesis. J Neurosci.,
22:2255-64. 2002
Histone deacetylase activity is necessary for oligodendrocyte lineage
progression. J Neurosci., 22:10333-45. 2002. |
PAUL R. COPELAND |
Associate Professor of Molecular
Genetics, Microbiology and Immunology, UMDNJ; Ph.D. University of
Virginia. Post-transcriptional gene regulation: Molecular biology
of selenium utilization. Insights into mammalian selenocysteine
incorporation: Domain structure and ribosome binding of SBP2. Mol.
Cell Biol. 21:1491-1498. |
SIOBHAN A. CORBETT |
Associate Professor
of Surgery, UMDNJ; M.D., Robert Wood Johnson Medical School.De novo
expression of the integrin alpha5beta1 regulates alphavbeta3-mediated
adhesion and migration on fibrinogen. J. Biol. Chem. 278:21878-21885,
2003. |
KIRON M. DAS |
Professor of Medicine, Molecular
Genetics and Microbiology, UMDNJ; M.D., Ph.D., Calcutta. Immunopathology
of ulcerative colitis and Crohn’s disease, specific tissue
antigens, autoimmunity, molecular studies. Gastroenterology, 109:3-12,
1995. |
DAVID T. DENHARDT |
Professor II, Department
of Cell Biology and Neuroscience, Rutgers University. Ph.D., California
Institute of Technology.Systems biology of osteopontin and TIMP-1:
Roles in cancer and bone biology - structure, function and signaling.
Homing of stem cells to tumors.
Osteopontin as a means to cope with environmental insults: regulation
of inflammation, tissue remodeling, and cell survival. J Clin Invest.
107(9):1055-1061. 2001
Tissue inhibitor of metalloproteinase-1 stimulates proliferation
of human cancer cells by inhibiting a metalloproteinase. Br J Cancer.
90(2):463-470. 2004 |
HUIZHOU FAN |
Assistant Professor
of Physics and Biophysics, UMDNJ; M.D., Ph.D.,Hunan Medical University,
China, University of Manitoba, Canada. The tetraspanin CD9 associates
with transmembrane TGF-a and regulates TGF-a-induced EGFR activation
and cell proliferation. J. Cell. Biol., 148:591-602. |
DAVID J. FORAN |
Professor of Pathology & Radiology,
UMDNJ; Ph.D., Rutgers University & University of Medicine and
Dentistry of New Jersey. Statistical pattern recognition, computer-based
image interpretation, and informatics as they relate to investigative
research in pathology and oncology. Unsupervised tissue microarray
analysis for cancer research and diagnostics. IEEE Transactions
on Information Technology in Biomedicine. 8:89-96. 2004. |
RAMSEY A. FOTY |
Assistant Professor
of Surgery, UMDNJ; Ph.D., University of Toronto, Canada. Cell adhesion
in development and cancer.Cadherin-mediated cell-cell adhesion and
tissue segregation in relation to malignancy. Int. J. Dev. Biol.
48:397-409. (2004). |
ABRAM GABRIEL |
Associate Professor of Molecular
Biology and Biochemistry, Rutgers University; M.D., M.P.H., Johns
Hopkins School of Medicine.Reverse transcriptases, retro transposons,
DNA repair, yeast, trypanosomes. “Retrotransposan reverse
transcriptase-mediated repair of chromosomal breaks”
Nature 383:641-44, 1996. |
MARC GARTENBERG |
Professor of Pharmacology,
RWJMS, Ph.D., Yale. Chromatin structure, gene regulation, and epigenetic
inheritance in yeast. Sir-mediated repression can occur independently
of chromosomal and subnuclear contexts (2004) Cell 119:955-967.
|
CELINE GELINAS |
Professor, Center for Advanced Biotechnology
and Medicine and RWJMS, Department of Biochemistry; Ph.D. Universite`
de Sherbrooke, PQ Canada. Oncogenes, malignant transformation, transcription,
cell proliferation, apoptosis. Zong, W.X., Farrell, M., Bash J.,
and Gelinas, C. (1997) v-Rel prevents apoptosis in transformed lymphoid
cells and blocks TNFalpha-induced cell death. Oncogene 15:971-980. |
F. JOSEPH GERMINO |
Associate Professor,
Cancer Institute of New Jersey, Department of Infectious Medicine-RWJMS;
M.D./Ph.D., Duke University. Protein-protein interactions, cell
cycle control; Gene, 173:146-154 1996. Oncology Res. 8:343-352,
1996. |
BEATRICE HAIMOVICH |
Associate Professor,
of Surgery and Biochemistry, RWJMS; Ph.D., University of Pennsylvania.
Tyrosine Phosphorylation of Alpha-Actinin in Activated Platelets.
J. Biol. Chem., 274:37012-37020, 1999. Neutrophil adhesion to vascular
prosthetic surfaces triggers nonapoptotic cell death. Ann Surg.
2000 Apr;231(4):587-99. PMID: 10749621: UI: 20213225 |
MICHAEL HAMPSEY |
Professor of Biochemistry, UMDNJ;
Ph.D., Purdue University. Regulatim of gene expression; yeast genetics.
“An activation-specific role for transcription factor TFIIB
in vivo.” Proc. Natl. Acad. Sci. 96:2764-2769, 1999. |
CHARLES WILLIAM
HEWITT |
Associate Professor
of Surgery, RWJMS at Camden; Ph.D., Pathology, University of Southern
California. Vascularized bone marrow, composite tissue, and extremity
transplantation, bioengineering of artificial tissues, as burn,
injury, and disease models; site-specific immune modulation; mechanisms
of chimerism, immune tolerance and immune suppression; consequences
of trauma induced immune modulation; immunopharmacology; transplantation
immunology. |
MASAYORI INOUYE |
Professor of Biochemistry, UMDNJ;
Ph.D., Osaka University, Osaka, Japan. Cold-shock response and adaptation;
Stress response through histidine kinases; Intramolecular chaperone-protein
memory; Bacterial retroelements.Spontaneous subunit exchange and
biochemical evidence for trans-autophosphorylation in a dimer of
Escherichia coli histident kinase (EnvZ) J. of Mol. Biol. 329:495-503,
2003. |
WILLIAM G. JOHNSON |
Professor of Neurology,
RWJMS; M.D., Columbia University College of P&S. Genetics of
Human Neurological Disorders: Parkinson’s disease, epilepsy,
schizophrenia, human developmental disorders. Science 276: 2045-2047,
1997. |
TERRI GOSS KINZY |
Professor of Molecular Genetics, Microbiology
and Immunology, UMDNJ RWJMS; Ph.D., Case Western Reserve University.Mechanism
and regulation of gene expression during protein synthesis. Nature
Struct. Biol.10:379-385, 2003; J. Biol. Chem. 278:6985-6991, 2003. |
JOACHIM B. KOHN |
Professor of Chemistry;
Ph.D., Weizman Institute (Israel).New approaches to biomaterials
design. Nature Materials, 3:745-747, 2004. |
SUNITA GUPTA KRAMER |
Assistant Professor of Pathology and
Laboratory Medicine, RWJMS; Ph.D. State University of New York @
Stony Brook.Directed cell migration during Drosophila development.
Patterning of the embryonic heart and body wall muscles.Switching
repulsion to attraction: changing responses to Slit during transition
in mesoderm migration. Science 292(5517):737-740, 2001. |
JEROME A. LANGER |
Associate Professor
of Molecular Genetics, Microbiology and Immunology, UMDNJ; Ph.D.,
Yale. Interferon and Interferon receptors. FEBS Letters, 350:281-286,
1994. |
EDMUND C. LATTIME |
Professor of Surgery, Molecular Genetics,
Microbiology and Immunology, UMDNJ and Associate Director, Cancer
Institute of New Jersey; Ph.D., Rutgers University. Tumor-induced
IL-10 Suppresses the Ability of Splenic Dendritic Cells to Stimulate
CD4 and CD8 T Cell Responses. Cancer Res. 63:2150-2157. 2003.Intratumoral
vaccination with vaccinia expressed tumor antigen and GM-CSF overcomes
immunological ignorance to tumor antigen. Cancer Res. 63:6956-6961.
2003 |
MICHAEL J. LEIBOWITZ |
Professor of Molecular
Genetics, Microbiology and Immunology, UMDNJ; M.D., Ph.D., Albert
Einstein.Molecular biology of prions and amyloids, new approaches
to drug delivery. Bioreversible disulfide linkage of thioamide compounds
to thiol-poly(ethylene glycol): application to UC781, an inhibitor
of HIV-1 reverse transcriptase. J. of Applied Therapeutic Res.,
4:46-53 2004. |
JOHN LENARD |
Professor of Physiology and Biophysics,
RWJMS; Ph.D. , Cornell.Long-term effects of sterol deprivation in
C. elegans: sterol content of synchronized wild-type and mutant
populations. J. Lipid Res. 45:2044-2051. 2004. |
HONGHUA LI |
Professor of Molecular
Genetics, Microbiology and Immunology, RWJMS at Cancer Institute
of New Jersey. Ph.D., University of Southern California. Genetic
basis of breast cancer and mechanisms underlying human immunoglobulin
heavy chain VH region divesification. J. Mol. Diagn. 2:29-36; Proc.
Natl. Acad. Sci. USA 95:10791-10796. |
LEROY FONG LIU |
Professor and Chair of Pharmacology,
UMDNJ; Ph.D., University of California, Berkeley. Cancer pharmacology,
DNA damage and repair, genome instability, Prog. in Nucl. Acid Res.
and Mol. Biol., 54:253-292, 1996. |
PETER LOBEL |
Professor, Department
of Pharmacology, UMDNJ; Ph.D., Columbia University.Association of
mutations in a lysosomal protein with classical late infantile neuronal
ceroid lipofuscinosis, Science, 277:1802-1805. 1997. |
JIANJIE MA |
Professor of Physiology and Biophysics,
UMDNJ; Ph.D., Baylor College of Medicine. Synergistic Movements
of Ca2+ and Bax in Cells Undergoing Apoptosis. J. Biol. Chem. 276:32257-32263. |
MICHAEL P. MATISE |
Assistant Professor
of Neuroscience & Cell Biology, UMDNJ; Ph.D., University of
Pittsburgh Medical School. Neuronal patterning and cell fate specification
in the developing spinal cord.Transduction of graded Hedgehog signaling
by a combination of Gli2 and Gli3 activator functions in the developing
spinal cord. Development 131:3593-3604. |
RANDALL D. MCKINNON |
Associate Professor of Surgery (Neurosurgery),
UMDNJ; Ph.D., McMaster University. CNS development; growth factors;
signal transduction. Wnt-mediated axon guidance via the Drosophila
Derailed receptor. Nature, 422: 583-588, 2003. |
JOACHIM W. MESSING |
Professor of Molecular
Biology and Director of the Waksman Institute; Ph.D., Munich. Regulation
of gene expression in higher plants; genomic imprinting and genomic
rearrangements. |
JAMES H. MILLONIG |
Assistant Professor of Physiology
and Neurobiology, UMDNJ, and Resident Member of the Center for Advanced
Biotechnology and Medicine. Ph.D., Princeton University. The Mouse
Dreher gene (Lmxla) Controls Formation of the Roof Plate Formation
in Vertebrate CNS. Nature 403:764-768, 2000. |
WILLIAM R. MOYLE |
Professor of Obstetrics
and Gynecology, UMDNJ; Ph.D., Harvard University. Functional homodimeric
glycoprotein hormones: implications for hormone action and evolution.
Chem. & Biol. 5:241-254, 1998. |
NICOLA C. PARTRIDGE |
Professor and Chair, Department of
Physiology and Biophysics, UMDNJ; Ph.D., University of Western Australia.
Hormonal regulation of gene transcription; matrix metalloproteinases
in bone and cartilage re-modelling. “Parathyroid hormone regulation
of the rat collagenase-3 promoter by protein kinase A-dependent
transactivation of core binding factor A1.” J. Biol. Chem.,
275:5037-5042, 2000. |
JOHN E. PINTAR |
Professor of Neuroscience and Cell
Biology, UMDNJ; Ph.D., University of Oregon. Genetic control of
mammalian growth and neuroendocrine function. “Developmental
expression of the mu, delta, and kappa opioid receptor mRNAs in
mouse.” J. Neuroscience 18:25-38, 1998. |
ARNOLD RABSON |
Professor of Molecular
Genetics, Microbiology and Immunology, UMDNJ, and Resident Member
of the Center for Advanced Biotechnology and Medicine. M.D., Brown
University.Selective infection of human T-lymphotropic virus type
1 (HTLV-1)-infected cells by chimeric human immunodeficiency viruses
containing HTLV-1 tax response elements in the long terminal repeat.
J Virol. 69:7216-7225. 1995 |
DANNY REINBERG |
Distinguished Professor, UMDNJ; Ph.D.,
Yeshiva , Albert Einstein. A Unified Theory of Gene Expression.
Cell 108:439-451, 2002 |
MICHAEL REISS |
Professor, UMDNJ;
Associate Director for Translational Research; Director, Breast Cancer
Research Program at The Cancer Institute of New Jersey; M.D., University
of Amsterdam. Role of Transforming Growth Factor B in Human Cancer.
TGF-B and Cancer. Microbes and Infection. 1999 1:1327-1347. |
YACOV RON |
Professor of Molecular Genetics, Microbiology
and Immunology, UMDNJ; Ph.D., Weizman Institute (Israel).Molecular
approaches for treatment of autoimmune disease via gene therapy;
B and T-cell development. Proc. Natl. Acad. Sci., USA, 91:8875. |
AMRIK SAHOTA |
Professor of Genetics,
RU; Ph.D. London University, (United Kingdom).Molecular Genetics and
Diagnostics.Impaired expression of an organic cation transporter,
IMPT1, in a knockout mouse model for kidney stone disease. Urol. Res.
31:257-261, 2003. |
AARON J. SHATKIN |
Professor of Molecular Genetics, Microbiology
and Immunology, UMDNJ, and Director of the Center for Advanced Biotechnology
and Medicine; Ph.D., Rockefeller.Eukaryotic gene expression; Viral
and cellular mRNA capping, Adv. Vir. Res. 55:135-184. |
MICHAEL M. SHEN |
Professor of Pediatrics,
and Resident Member of the Center for Advanced Biotechnology and
Medicine; Ph.D., Cambridge.A differential display strategy identified
Cryptic, a novel EGF-related gene expressed in the axial and lateral
mesoderm during mouse gastrulation. Development, 124:429-442. |
YUFANG SHI |
Professor of Molecular Genetics, Microbiology
& Immunology, RWJMS, Ph.D., University of Alberta.T cell immunology,
T cell apoptosis, T helper differentiation, psychoneuroimmunology,
bone-immune interaction. Reciprocal Expression of TRAIL and CD95L
in Th1 and Th2 Cells: Role of Apoptosis in T Helper Subset Differentiation.
Cell Death Differ 10:216-224. |
MARTHA SOTO |
Assistant Professor
of Pathology and Laboratory Medicine, RWJMS, Ph.D. Harvard Medical
School.Cell polarity and regulation of cytoskeletal dynamics during
C. elegans development.The GEX-2 and GEX-3 proteins are required for
tissue morphogenesis and cell migrations in C. elegans. Genes &
Development 16:620-632, 2002. |
STANLEY STEIN |
Adjunct Professor of Molecular Genetics,
Microbiology and Immunology, UMDNJ, and Research Professor, Ernest
Mario School of Pharmacy; Ph.D., CUNY. Protein and Peptide therapeutics.A
hydrogel prepared by in situ cross-linking of a thiol-containing
poly(ethylene glycol)-based copolymer: a new biomaterial for protein
drug delivery. Biomaterials 24:11-18 2003. |
ANN STOCK |
Professor of Biochemistry,
UMDNJ; Investigator of the Howard Hughes Medical Institute, and Member
of the Center for Advanced Biotechnology and Medicine; Ph.D., Berkeley.
Structure/function analysis of signal transduction proteins. Structural
analysis of the domain interface in DrrB, a response regulator of
the OmpR/PhoB subfamily. J. Bacteriol. 185:4186-4194. 2003 |
VICTOR STOLLAR |
Professor of Molecular Genetics, Microbiology
and Immunology, UMDNJ; M.D., Queens, Ontario. Mosquito-transmitted
viruses; viral genetics, biochemistry of viral replication. Complementation
of and interference with Sindbis virus replication by full length
and deleted forms of the nonstructural protein nsP1, expressed in
stable transfectants of Hela cells. Virology, 227:361-369, 1997. |
ROGER K. STRAIR |
Associate Professor
of Medicine, UMDNJ-The Cancer Institute of New Jersey; M.D., Ph.D.,
Albert Einstein. Cellular and genetic approaches to hematopoietic
stem cell manipulation. AIDS Res. Hum. Retroviruses, 12:965-968. |
NANCY C. WALWORTH |
Professor of Pharmacology, UMDNJ; Ph.D.,
Yale University.A novel protein with similarities to Rb binding
protein 2 compensates for loss of Chk1 function and affects histone
modification in fission yeast. Molecular and Cellular Biology 24(9):3660-3669,
2004. |
GUY WERLEN |
Associate Professor
of Biology, Rutgers University, Ph.D., University of Geneva, Switzerland
Signal transduction in T lymphocyte development and activation.
Signaling life and death in the thymus: timing is everything. Science,
299(5614): 1859-1863, 2003. |
DONALD A. WINKELMANN |
Professor of Pathology and Laboratory
Medicine, UMDNJ; Ph.D., University of Wisconsin. Macromolecular
structure and assembly, molecular motors, the cytoskeleton.
“Glycine 699 is pivotal for the motor activity of skeletal
muscle.” The Rockefeller University Press - The J. of Cell
Biol. V. 134, No. 4, (8/96) |
MENGQING XIANG |
Assistant Professor,
Department of Pediatrics, UMDNJ. Ph.D., University of Texas, M.D.,
Anderson Cancer Center, Houston, Texas. Molecular neurodevelopment. |
PETER D. YURCHENCO |
Professor of Pathology and Laboratory
Medicine, UMDNJ; M.D., Ph.D., Albert Einstein College of Medicine.
Role of laminins in epithelial polarization and tissue organization
during embryogenesis. Dev. Cell. 4:613-624. 2003. |
JAMES Q. ZHENG |
Professor, Department
of Neuroscience & Cell Biology, UMDNJ; Ph.D., Tsinghua University.
A CaMKII/Calcineurin Switch Controls the Direction of Ca2+-dependent
Growth Cone Guidance, Neuron 43:835-846, 2004.Lipid Rafts Mediate
Chemotropic Guidance of Nerve Growth Cones. Neuron 42:51-62, 2004 |
X. F. STEVEN ZHENG |
University Professor, Department of
Pharmacology, UMDNJ, Ph.D., Harvard University Growth control, Signal
transduction, Cancer, chromatin regulation, Yeast.
“Chromatin-mediated regulation of nucleolar structure and
RNA Polymerase I localization by TOR”, EMBO J 22:6045-6056. |
