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Faculty Profile
Alan Gelperin

Professor

Ph D University of Pennsylvania

 



Dept. of Neuroscience
University of Pennsylvania School of Medicine

Monell Chemical Senses Center
3500 Market Street
Philadelphia, PA 19104

Tel: 215 898-5885
FAX: 215 898-2084

agelperin@monell.org

Webpage

 
Research Interests Research Techniques
Cellular and computational analysis of olfactory information processing and learning in mammals and mollusks  

Research Summary

My laboratory studies odor information processing and memory storage in biological, computational and electronic olfactory systems. We study biological olfaction using mammalian and molluscan model systems whose central odor processing networks reliably learn complex predictive relationships between odor and taste stimuli. We use electrical and optical recording methods to understand the role of oscillatory dynamics and neurogenesis in odor recognition and memory storage. Computational methods are used to generate biophysically-based network models of the olfactory system to identify general design principles shared by mollusks and mammals. With collaborators in electronic olfaction we work on developing new sensor arrays, new sensor circuits and new algorithms to enable an autonomous robot fitted with an electronic nose to localize odor sources.

 

Key References

For complete list: PubMed

Gelperin, A. (2002) Invertebrate Learning: Associative learrning in Limax. In: Learrning and Memory, 2nd. Edition, Ed. J. Byrne, Macmillian Pub. Co., NY, pp. 281-287.

Gelperin, A. and Hopfield, J.J. (2002) Electronic and computational olfaction. In P. Given (ed.) Chemistry of Taste, American Chemical Society, Washington, DC., pp.289-317

Crone, B., Dodabalapur, A., Gelperin, A., Torsi, L., Katz, H.E., Lovinger, R., Bao, Z. (2001) Odor sensing and recognition with organic field-effect sensors and circuits. Applied Physics Letters78: 2229-2231.

Gelperin, A. (2001) Smelling well with a code in the nodes. Neuron 30: 307-309.

Gelperin, A., Kao, J.P.Y. and Cooke, I.R.C.. (2001). Gaseous oxides and olfactory computation. Amer. Zool. 41:332-345.

Fujie, S., Aonuma, H., Ito, I., Gelperin, A., Ito, E. (2002) The nitric oxide/cyclic GMP pathway in the olfactory processing system of the terrestrial slug Limax marginatus. Zool. Sci. 19:15-26.