UMDNJ - ROBERT WOOD JOHNSON MEDICAL SCHOOL
DEPARTMENT OF PATHOLOGY AND LABORATORY MEDICINE

Administrative: Acting Director, Child Health Institute of New Jersey

Department: Pathology and Laboratory Medicine

Lab Url:  http://www2.umdnj.edu/chinjweb/rlt.htm

Phone Number: (732) 235-9525 

Fax Number: (732) 235-9333 

Child Health Institute
Liberty Plaza
New Brunswick, New Jersey 08903-0019

1972

Corneal Task Force, National Eye Institute, NIH

1975-1976

Ad Hoc Member, Cell Biology Study Section, NIH

1977

Ad Hoc Member, Pathobiological Chemistry Study Section, NIH

1977-1981

Cell Biology Study Section, NIH

1978

External Review Committee, Laboratory for Developmental Biology and Craniofacial Anomalies, NIH

1981

Panel on Congenital Anomalies and Acquired Defects, NIH

1981-1987

American Society for Cell Biology, Executive Council

1981-1987

Secretary, American Society for Cell Biology

1981-1984

Society for Developmental Biology, Board President, 1982-1983

1982

Fogarty International Awards Review Group, NIH

1983-1987

Scientific Advisory Board, Shriners Hospitals for Crippled Children

1984-1988

Maternal and Child Health Research Committee, NICHHD

1986-1989

Chairman, Site Visit Sub-committeeS, NICHHD

1986-1989

Research Peer Review Committee, American Heart Association - NJ

1987-1991

National Board of Medical Examiners, Pathology Section

1990-1993

American Society for Clinical Pathology
Commission on Graduate Medical Education in Pathology Council on Education and Research

1990-1998

Executive Committee, Universities Associated for Research and   Education in Pathology

1993-1997

Advisory Council, National Institute of Child Health and Human Development, NIH

1994-1998

Advisory Committee, Registry of Comparative Pathology, Armed Forces Institute of Pathology, Washington, DC

1997

Ethics in Genetics Research Subcommittee, FASEB

1999   

American Society for Cell Biology, 40th Anniversary Committee

2000 

Chair, ad hoc Study Section on Developmental Mechanisms of Human Malformation

2001  

Chair, ad hoc Study Section on Human Embryo Sections on DVDs for Education

1. Trelstad RL. Double Isotope Autoradiography. Exp Cell Res 39:318-328, l965.  

2. Trelstad RL, Revel JP, Hay ED. Tight junctions between cells in the early chick embryo as visualized  with the electron microscope.  J Cell Biol  31:C6-10, 1966.  

3. Trelstad RL, Revel JP, Hay ED. Cell contact in early embryonic chick morphogenesis as studied with the  electron microscope.  Develop Biol 16:78-106, 1967. (ISI Citation Classic).

4. Trelstad RL. The New Harvard Curriculum. Pre-Med. 7:15-18, 1968.  

5. Trelstad RL. The effect of pH on the stability of purified glutaraldehyde. J Histochem Cytochem 17:756- 757, 1969.  

6. Trelstad RL. The Golgi apparatus in chick corneal epithelium: Changes in intracellular position during  development.  J Cell Biol 45:34-42, 1970.  

7. Willerson JT, Trelstad RL, Pincus T, Levy SB, Wolff SM. Subcellular localization of S. enteriditis  endotoxin in liver and spleen of mice and rats.  Infection and Immunity 1:440-445, 1970.  

8. Trelstad RL, Kang AH, Igarashi S, Gross J. Isolation of two distinct collagens from chick cartilage.  Biochem 9:4993-4998, 1970.  

9. Trelstad RL. Vacuoles in the embryonic chick corneal epithelium an epithelium which produces collagen. J  Cell Biol 48:689-694, 1971.  

10. Trelstad RL, Coulombre AJ. Morphogenesis of the collagenous stroma in the chick cornea.  J Cell Biol  50:840-858, 1971.  

11. Toole BP, Trelstad RL. Hyaluronate production and removal during corneal development in the chick.   Develop. Biol. 26:28-35, 1971.  

12. Harthorne W, Trelstad RL.  Case Records of the Massachusetts General Hospital, New Engl. J. Med.  284:120l-1204, 1971.  

13. Gross J, Trelstad RL, Kang AH, Toole BP, Igarashi, S. Heterogeneity of collagen molecules.  Israel J.  Med. Sci. 7:453-454, 1971.  

14. Toole BP, Kang AH, Trelstad RL, Gross, J. Collagen heterogeneity within different growth regions of  long bones of rachitic and non-rachitic chicks. Biochem. J. 127:715-720, 1972.  

15. Trelstad RL. The comparative molecular biology of extracellular matrices. Slavkin, H.C. ed. Academic  Press, N.Y., pp. 100-8, 420-1, 1972.  

16. Trelstad RL, Kang AH, Toole BP, Gross, J.  Collagen heterogeneity: High resolution separation of  native Type I and Type II and their component chains. J Biol Chem 247:6469-6473, 1972.  

17. Trelstad RL, Kang AH, Cohen AM, Hay ED. Collagen synthesis in vitro by embryonic spinal cord  epithelium. Science 179:295-297, 1973.  

18. Igarashi S, Trelstad RL, Kang AH. Physical chemical properties of chick cartilage collagen. Biochem  Biophys Acta 295:514-519, 1973.  

19. Kang AH, Trelstad RL. A Collagen defect in homocystinuria.  J Clin Invest 52:2571-2578, 1973.  

20. Trelstad RL. The developmental biology of vertebrate collagens J Histochem Cytochem 21:521-528,  1973.  

21. Bruns RR, Trelstad RL, Gross J. Cartilage collagen: A staggered substructure in reconstituted fibrils.   Science 181:269-271, 1973.  

22. Linsenmayer TF, Trelstad RL, Toole BP, Gross, J. The collagen of osteogenic cartilage in the  embryonic chick. Biochem Biophys Res Commun 52:870-876, 1973.  

23. Linsenmayer TF, Trelstad RL, Gross J. The collagen of chick embryonic notochord. Biochem Biophys  Res Commun 53:39-45, 1973.  

24. Linsenmayer TF, Toole BP, Trelstad RL. Temporal and spatial transitions in collagen types during  embryonic chick limb development. Develop Biol 35:232-239, 1973.  

25. Mills JA, Trelstad RL. Polymyalgia Rheumatica. Case records of the Massachusetts General Hospital.  New Eng J Med 289:311-316, 1973.  

26. Trelstad RL, Kang AH. Collagen heterogeneity in the avian eye: Lens, vitreous body, cornea and sclera.  Exp Eye Res 18:395-406, 1974.  

27. Trelstad RL. Human aorta collagens. Evidence for three distinct species. Biochem Biophys Res  Commun  57:717-725, 1974.  

28. Trelstad RL, Slavkin HC. Collagen synthesis by the epithelium enamel organ of the embryonic rabbit  tooth. Biochem Biophys Res Commun 59:443-449, 1974.  

29. Trelstad RL. Vertebrate collagen heterogeneity:  A brief summary.  Develop Biol 38:f13-16, 1974.  

30. Trelstad RL, Hayashi K, Toole BP. Epithelial collagens and glycosaminoglycans in the embryonic  cornea. J Cell Biol 62:815-830, 1974.  

31. Trelstad RL. Collagen fibrillogenesis in vitro and in vivo. The existence of unique aggregates and the  special state of the fibril end. In: 'Extracellular Matrix Influences on Gene Expression', Slavkin HC,  Greulich RC eds. Academic Press, pp 331-339, 1975.  

32. Trelstad RL. Cell polarity in the early chick mesoderm. In: 'Communications of International  Symposium on Early Avian Development', Vakaet L, ed. Rijksuniversitar Centrum Antwerpen pp  135-147, 1975.  

33. Hayashi K, Trelstad RL. A simplified dipping method for electron microscope auto  ography. Stain  Tech 51:68-69, 1976.  

34. Trelstad RL, Lawley KR. A simple economical buffer system for amino acid analysis. Anal Biochem  70:287-289, 1976.  

35. Trelstad RL, Catanese VM, Rubin DF. Collagen fractionation: Separation of native types I, II and III by  differential precipitation. Anal Biochem 71:114-118, 1976.  

36. Newsome DA, Linsenmayer TF, Trelstad RL. Vitreous body collagen: Evidence for a dual origin from  the neural retina and hyalocytes. J Cell Biol 71:59-67, 1976.  

37. Trelstad RL, Hayashi K, Gross J. Collagen fibrillogenesis: Intermediate aggregates and suprafibrillar  order. Proc Nat'l Acad Sci US 73:4027-4031, 1976.  

38. Trelstad RL, Holmes LB. Cellular polarity at the epithelial mesenchymal interface. 1976. Proceedings,  International Conference on Cholesteatoma. Aesculapius Publishing Co, pp 62-65.

39. Burke JF, Quinby WC, Bondoc C, McLaughlin E, Trelstad RL. Patterns of high tension electrical injury  in children and adolescents and their management. Amer J Surg 133:492-497, 1977.  

40. Trelstad RL, Rubin DF, Gross J. Osteogenesis imperfecta congenita: Evidence for a generalized  molecular disorder of collagen. Lab Invest 36:501-508, 1977.  

41. Trelstad RL, Lawley KR. Isolation and initial characterization of human basement membrane collagens.  Biochem Biophys Res Commun 76:376-384, 1977.  

42. von der Mark K, von der Mark H, Timpl R, Trelstad RL.  Immunofluorescent localization of collagen  types I, II and III in the embryonic chick eye. Develop Biol 59:75-85, 1977.  

43. Holmes LB, Trelstad RL. Patterns of cell polarity in the developing mouse limb. Develop Biol 59:164- 173, 1977.  

44. Trelstad RL. Mesenchymal cell polarity and morphogenesis of chick cartilage. Develop Biol 59:153-163,  1977.  

45. Trelstad RL, Lawley KR, Hayashi K. Isolation of basement membrane collagens using a new heat gel  fractionation method. In: Symposium on the Biology and Chemistry of Basement Membranes.  Kefalides NA, ed. Academic Press, 1978, pp 229-233.  

46. Trelstad RL. Amino Acid Analysis of Collagen. Application Data, DS-526, Beckman Instruments, Inc.  1978.  

47. Trelstad RL. The special state of the fibril end: Site of growth, point of cell surface attachment and  possible site for platelet interaction. Suppl- Thromb-Haemost. 1978. 63. P 153-60. and In:  'Collagen-Platelet Interaction' Gastpar H, ed. FK Schattauer Verlag, Stuttgart-New York, 1978, pp  153-160.  

48. Zaki MS, Burke JF, Trelstad RL. Protective effects of adenosine triphosphate administration in burns.  Arch Surg 113:605-610, 1978.  

49. Sandstrom RE, Proppe KH, Trelstad RL. Fibrous histiocytoma of the trachea. Amer J Clin Path 70:97- 10l, 1978.  

50. Kitajima M, Wolfe RR, Trelstad RL, Allsop JR, Burke JF. Gastric mucosal lesions after burn injury:  Relationship to H~+~ back-diffusion and the microcirculation. J Trauma 18:644-650, 1978.  

51. Quinby WC, Burke JF, Trelstad RL, Caulfield J. The use of microscopy as a guide to primary excision  of high-tension electrical burns. J Trauma 18:423-431, 1978. 

52. Hay ED, Linsenmayer TF, Trelstad RL, von der Mark K. Origin and distribution of collagen in the  developing avian cornea. Current Topics in Eye Research. Zadunaisky J, Davson H, eds Academic  Press, 1979; Vol 1, pp 1-35.  

53. Quaroni A, Wands J, Trelstad RL, Isselbacher KJ. Epithelioid cell cultures from rat small intestine.  Characterization by morphological and immunologic criteria. J Cell Biol 80:248-265, 1979.  

54. Krane SM, Trelstad RL. A young man with abnormalities of skin and joints and intra-abdominal  hemorrhage: Case Records of the Mass General Hospital. New Engl J Med 200:129-235, 1979.  

55. Harrist TJ, Schiller AL, Trelstad RL, Mankin HJ, Hays CW.  Thoratrast-associated sarcoma of bone.  Cancer 44:2049-2058, 1979.  

56. Zapol WM,Trelstad RL, Coffey JW, Tsai I, Salvador RA. Pulmonary fibrosis insevere acute respiratory  failure. Amer Rev of Resp Disease 199:547-554,l979.

57. Trelstad RL, Carvalho A. Type IV and Type A-B collagens do not elicit platelet aggregation or the  serotonin release reaction. J Lab Clin Med 93:499-505, 1979.  

58. Trelstad RL, Hayashi K. Tendon fibrillogenesis: Intracellular collagen subassemblies and cell surface  changes associated with fibril growth. Develop Biol 71:228-242, 1979.  

59. Wolfe RR, Hochachka PW, Trelstad RL, Burke JF. Lactate oxidation in the perfused rat lung. Amer J  Physiol 236:E276-E282, 1979.  

60. Silver FH, Langley KH, Trelstad RL. Type I collagen fibrillogenesis: Initiation via a reversible linear  growth step Biopolymers 18:2523-2535, 1979.  

61. Holmes LB, Trelstad RL. The early limb deformity caused by acetazolamide. Teratology 20:289-296,  1979.  

62. Holmes LB, Trelstad RL. Identification of rapidly labeled small molecular weight hydroxyproline- containing peptides in developing mouse limbs in vitro and in vivo. Develop Biol 72:41-49, 1979.  

63. Harris ED, Trelstad RL. A 24-year old man with swelling of the hands and feet and eosinophilia: Case  Records of the Massachusetts General Hospital. New Engl J Med 301:256-263, 1979.  

64. Trelstad RL. Basement membrane collagens: Unusual interactive properties. In: 'Biochemistry and  Pathology of Basement Membranes' Robert AM, Boniface R, Robert L. eds. Frontiers of Matrix  Biology, S Karger, Basel 7:9-18,l979.  

65. Silver FH, Trelstad RL. Linear aggregation and the turbidimetric lag phase: Type I collagen  fibrillogenesis in vitro. J Theor Biol 81:515-526, 1979.  

66. Li KC, Ehrlich HP, Trelstad RL, Koroly MJ, Schattenkerk ME, Malt RA. Differences in healing of skin  wounds caused by burn and freeze injuries. Annals of Surgery 191:244-248, 1980  

67. Holmes LB, Trelstad RL. Cell polarity in precartilage mouse limb mesenchyme cells. Develop Biol  78:511-520, 1980.  

68. Quaroni A, Trelstad RL. Biochemical characterization of collagens synthesized by intestinal epithelial cell  cultures. J Biol Chem 255:8351- 8361, 1980.  

69. Silver FH, Trelstad RL. Type I collagen in solution: Structure and properties of fibril fragments. J Biol  Chem 255:9427-9433, 1980.  

70. Silver FH, Trelstad RL. Physical properties of type I collagen in solution: Structure of alpha chains and  beta and gamma components. Biopolymers 20:359-371, 1981.  

71. Trelstad RL, Lawley KR, Hayashi K, Ehrlich HP, Silver FH. Type V collagen from the chick embryo:  Biochemical, physicochemical and ultrastructural characteristics. Collagen and Related Research  1:39- 52, 1981  

72. Ehrlich HP, Trelstad RL, Fallon JT. Dermal vascular patterns in response to burn or freeze injury in  rats. Exper and Mole Pathology 34:281-289, 1981.  

73. Trelstad RL, Lawley KL, Holmes LB. Non-enzymatic hydroxylations of proline and lysine in free and  polypeptide form by reduced oxygen derivatives. Nature 289:310-312, 1981.  

74. Strole WE, Harrist TJ, Trelstad RL. Defects in liver scans 29 years after injection of Thorotrast. Case  records of the Massachusetts General Hospital. New Eng J Med 304:893-899, 1981.  

75. Donahoe PK, Budzik GP, Trelstad RL, Mudgett-Hunter M, Fuller AF, Jr Hutson JM, Ikawa H,  Hayashi H, MacLaughlin D. Mullerian Inhibiting Substance: An update. Greep RO, ed. Recent  Progress in  Hormone Research, Volume 38. New York: Academic Press, 1982, pp 279-330.  

76. Casper DS, Trelstad RL, Reif-Lehrer L. Glutamate-induced cellular injury in isolated chick embyro  retina: Muller Cell localization of initial effects. J Comp Neurol, 209:79-90, 1982.  

77. Casper DS, Trelstad RL, Reif-Lehrer L. Age dependent effects of glutamate on photoreceptor cells of the  isolated chick embryo retina. J Neuropath & Exp Neurol, 41:522-535, 1982.  

78. Trelstad RL, Silver FH. Matrix Assembly  In: 'Cell Biology of Extracellular Matrix', Hay ED, ed.  Plenum Press, 1982, pp 179-215.  

79. Trelstad RL. Native Collagen Fractionation In: Immunochemistry of the Extracellular Matrix, Volume I,  Methods, Furthmayr H, ed, CRC Press, Inc., 1982, pp 31-41.  

80. Hayashi A, Donhoe PK, Budzik GP, Trelstad RL.:  Basement membrane and matrix glycosaminoglycan  turnover during rat Mullerian duct development. Develop Biol, 92:16-26, 1982.  

81. Trelstad RL, Birk DE, Silver FH. Collagen fibrillogenesis in tissues, solution and from modeling: A  synthesis. J Invest Derm, 79:109s-112s, 1982.  

82. Trelstad RL, Hayashi A, Hayashi K, Donahoe PK.  The epithelial-mesenchymal interface of the male rat  Mullerian duct: Loss of basement membrane integrity and ductal regression. Develop Biol, 92:27-40,  1982.  

83. Trelstad RL, Silbermann NN, Brockhurst RJ. Nanophthalmic sclera: Ultrastructural, histochemical and  biochemical observations. Arch of Ophthal 100:1935-1938, 1982.  

84. von Oeyen P, Holmes LB, Trelstad RL, Griscom NT. Omphalocele and multiple severe congenital  anomalies associated with osteodysplasty (Melnick-Needles syndrome). Amer J Med Genetics  13:453-458, 1982.  

85. Trelstad RL. Multistep assembly of Type I collagen fibrils.  Cell 28:197-198, 1982. 

86. Trelstad RL. The bilaterally asymmetrical architecture of the submammalian corneal stroma resembles a  cholesteric liquid crystal. Dev Biol, 92:133- 134, 1982.  

87. Bender E, Silver FH, Hayashi K, Trelstad RL. Type I Collagen SLS Banding Patterns: Evidence that  the alpha 2 chain is in the reference or 'A' position. J Biol Chem. 257:9653-9657, 1982.  

88. Trelstad RL, Birk DB, Silver FH. Cellular and collagen fibrillar polarity in developing chick limb  tendon. Prog-Clin-Biol-Res 1983 110 Pt A:245-9 and In: Limb Development and Regeneration.  Fallon JF, Caplan AI, eds. Alan R. Liss, Inc. New York, 1983, pp 245-249.  

89. Ehrlich HP, Buttle DJ, Trelstad RL, Hayashi K. Epidermolysis bullosa dystrophica recessive fibroblasts  altered behavior within a collagen matrix. J Invest Dermatology. 80: 56-60, 1983.  

90. Zapol WM, Trelstad RL, Snider MT, Pontoppidan H, Lemaire F. Pathophysiologic pathways of the  Adult Respiratory Distress Syndrome. In: 'Care of Critically Ill Patient', Tinker J, Rapin M, eds,  Springer Verlag, 1983, pp 341-358.  

91. Ikawa H, Trelstad RL, Hutson JM, Manganaro TF, Donahoe PK. Changing patterns of fibronectin,  laminin, type IV collagen and a basement membrane proteoglycan during Mullerian duct regression.  Dev Biol 102:260-263, 1984.  

92. Hayashi M, Shima H, Hayashi K, Trelstad RL, Donahoe PK.  Immunocytochemical localization of  Mullerian inhibiting substance in the rough endoplasmic reticulum and Golgi apparatus in Sertoli  cells of neonatal calf testis using a monoclonal antibody. J Histochem Cytochem. 32:649-654, 1984.  

93. Chandrasekhar S, Kleinman HK, Hassell JR, Martin GR, Termine JD, Trelstad RL. Regulation of type  I collagen fibril assembly by link protein and proteoglycans. Collagen and Related Res. 4:323-327,  1984.  

94. Trelstad RL and Birk DE. Cell polarity and collagen fibrillogenesis during morphogenesis of the tendon  and corneal stroma in the chick. In: 'The Role of the Extracellular Matrix in Development', Trelstad  RL ed. AR Liss,Inc, New York, 1984, pp 513-543.  

95. Donahoe PK, Hutson JM, Ikawa H, Schwartz BR, Budzik G, Trelstad RL. Molecular dissection of  Mullerian duct regression. In: 'The Role of Extracellular Matrix in Development', Trelstad RL, ed.  AR  Liss, Inc New York, 1984, pp 573-595.  

96. Schwartz BR, Trelstad RL, Hutson JM, Ikawa H, Donahoe PK. Zinc chelation and Mullerian duct  regression. J Exp Path 1:143-156, 1984  

97. Miyahara M, Hayashi K, Berger J, Tanzawa K, Njieha FK, Trelstad RL, Prockop, DJ. Formation of  collagen fibres by enzymic cleavage of precursors of type I collagen in vitro. The sequence of  propeptide removal influences fibre diameter. J Biol Chem 259:9891-9898, 1984.  

98. Kerr JS, Riley DJ, Frank MM, Trelstad RL, Frankel HM. Reduction of chronic hypoxic pulmonary  hypertension in the rat by beta-aminoproprionitrile. J Appl Physiol. 57:1760-1766, 1984.  

99. Ji S, Cheng L, Ghosh A, Matschinsky F, Maliniak C, Trelstad RL. Histolgical and metabolic injuries of  rat liver following acetaminophen treatment in vivo and in vitro. The Toxicologist 4:44-51, 1984.  

100. Birk DE, Trelstad RL. Extracellular compartments in matrix morphogenesis: Collagen fibril, bundle  and lamellar formation by corneal fibroblasts. J Cell Biol 99:2024-2033, 1984.  

101. Trelstad RL, Martin EG, Zapol WM. Interstitial alterations following acute lung injury. In: Acute  Respiratory Failure. Zapol WM and Falke, KJ, eds, Lung Biology in Health and Disease. Lenfant  LC, ed. Marcel Dekker, Inc., New York, 1984.  

102. Birk, DE, Trelstad, RL. Fibroblasts compartmentalize the extracellular space to regulate and facilitate  collagen fibril, bundle and macro- aggregate formation. In: 'Extracellular Matrix: Structure and  Function', Reddi, AH, ed, AR Liss, Inc, New York, 1985.  

103. Trelstad RL, Birk DE. The fibroblast in morphogenesis and fibrosis: cell topography and surface- related functions. Ciba Found Symp 114: 4-19, 1985.  

104. Trelstad RL. Glycosaminoglycans: mortar, matrix, mentor. Lab Invest 53:1-4, 1985.  

105. Birk DE, Trelstad RL. Fibroblasts create compartments in the extracellular space where collagen

106. polymerizes into fibrils and fibrils associate into bundles. Ann NY Acad Sci.  460:258-66, 1985.

107. Hayashi M, Ninomiya Y, Parsons J, Hayashi K, Olsen BR, Trelstad. Differential localization of  mRNAs of collagen types I and II in chick fibroblasts, chondrocytes, and corneal cells by in situ  hybridization  using cDNA probes. J Cell Biol 102:2302-2309, 1986.  

108. Birk DE, Trelstad RL. Extracellular compartments in tendon morphogenesis: Collagen fibril, bundle  and macroaggregate formation. J Cell Biol 103:231- 240, 1986.  

109. Hembry RM, Bernanke DH, Hayashi K, Trelstad RL, Ehrlich HP. Morphological examination of  mesenchymal cells in healing wounds of normal and tight skin mice. Amer J Path 125:81-89, 1986.  

110. Trelstad RL. Molecular Biology of Extracellular Matrix: Strategy and redundancy. In 'Progress in  Developmental Biology, Part B', Slavkin H, ed. AR Liss, Inc, New York, 1986, pp 371-376.  

111. Trelstad RL, Hayashi M, Hayashi K, Birk DE. Fibrils, Fibonacci and fractals: Searching for rules and  rulers of morphogenesis in the orthogonal stroma of the chick cornea. In 'The Microenvironment and  Vision' Sheffield JB and Hilfer SR, eds. Springer-Verlag, New York, 1987, pp 1-27.  

112. Hayashi K, Hayashi M, Jalkanen M, Firestone JH, Trelstad RL, Bernfield, MR.  Immunocytochemistry of cell surface heparan sulfate proteoglycan in mouse tissues. A light and  electron microscopic study. J Histochem Cytochem. 35: 1079-1088, 1987.

113. Trelstad RL. The pulmonary interstitium: Septa, segments and signals. Advances in Microcirculation   17:1-9, 1987.

114. Trelstad RL. The extracellular matrix is a soluble and solid phase agonist and receptor. Archives of  Dermatology 124:706-708, 1988.

115. Birk DE, Trelstad RL. Extracellular matrix morphogenesis: HVEM analysis. Proc Elec Microsc Soc  Amer 45:574-577.

116. Hayashi M, Ninomiya Y, Hayashi K, Linsenmayer TF, Olsen BR, Trelstad RL. Secretion of collagen  types I and II by epithelial and endothelial cells in the developing chick cornea demonstrated by in  situ hybridization and immunochemistry. Development 103:23-36, 1988.  

117. Trelstad RL. Glycoproteins in the Extracellular Matrix: Agonists, Receptors, Receptors, Timers, History. Cell  Regulation 1: 31-38, 1988.  

118. Hayashi K, Hayshi M, Boutin E, Cunha GR, Bernfield MR, Trelstad RL. Hormonal modification of  epithelial differentiation and expression of cell surface heparan sulfate proteoglycan in the mouse  vaginal epithelium: Lab Invest 58:68-76, 1988.

119. McBride DJ, Silver FH, Trelstad RL. Structural and mechanical assessment of developing chick  tendon. Int J Biological Macromolecules. 10:193-200, 1988.

120. Birk DE, Zycband E, Trelstad RL. Collagen fibril and matrix assembly during morphogenesis. Proc  Elect Microsc Soc Amer 46:232-234, 1998

121. Geismar LS, Kerr JS, Trelstad RL, Riley, DJ.  Treatment of Experimental Silicosis with Antifibrotic  Agents. Toxicology 53:33l-344, l988.

122. Trelstad RL. Matrix Glycoproteins. In: "Textbook of Rheumatology" Kelley WN, Harris ED, Jr.,  Ruddy S, Sledge CB (eds). WB Saunders Co, New York 1989, pp. 42-53.

123. Raskova J, Martin EG, Trelstad RL, Shea SM. Independent Learning in Pathology. Does it Work?  Arch Pathol Lab Med 113:204-206, 1989.

124. Birk DE, Zycband EI, Winkelmann DA, Trelstad RL. Collagen fibrillogenesis in situ: Fibril segments  are intermediates in matrix assembly. Proc Nat'l Acad Sci USA 86:4549-4553, l989.

125. Trelstad RL, Shea SM, Martin EG, Raskova J. Computer assisted pathology education. In:  "Computers in Health Sciences" Haque, S, ed. Dependable Press, Hyattsville, Maryland, 1989,  pp. 167-170.

126. Birk DE, Zycband EI, Southern J, Fallon JT, Trelstad, RL. Collagen fibril bundles: A branching  assembly unit in tendon morphogenesis. Development 107: 437-443, 1989.

127. Perche O, Hayashi M, Hayashi K, Birk D, Trelstad RL, Sandoz D. Origin of type I collagen localized  within oviduct epithelium of quail hyperstimulated by progesterone. J Cell Science 95: 85-95, 1990.

128. Gorstein F, Trelstad R: The pathologist as student and educator (editorial). Human Path 21:1-3, 1990.

129. Iyama K, Ninomiya Y, Olsen BR, Linsenmayer TF, Trelstad RL, Hayashi M. Shift in spatial pattern of  type X collagen expression in embryonic sterna undergoing endochondral ossification demonstrated  by in situ hybridization and immunochemistry. In: Structure, Molecular Biology and Pathology of  Collagen, Ann NY Acad Sci, 580:529-531, 1990.

130. Birk DE, Zycband EI, Winkelmann DA, Trelstad, RL. Collagen fibrillogenesis in situ: discontinuous  segmental assembly in extracellular compartments. In: Structure, Molecular Biology and Pathology  of Collagen, Ann NY Acad Sci, 580: 176-194, 1990.

131. Trelstad RL. Matrix macromolecules: Spatial relationships in two dimensions. In: Structure, Molecular  Biology and Pathology of Collagen, Ann NY Acad Sci, 580: 391-420, 1990.

132. Trelstad RL. Diagnostic Workstations in Pathology (editorial). Human Path 21:987-988, 1990  

133. Trelstad RL (editor), 'Pathology TextStack', a hypertext version of: Cotran R, Kumar V and Robbins  S. "Robbins Pathologic Basis of Disease" (W.B. Saunders, 4th Edition, 1989 & 5th Edition, 1994).  Keyboard Pathology Series,  Keyboard Publishing, Inc., 1989 & 1994

134. Trelstad RL (editor), 'Pathology VideoIndex', a hypertext guide to the 'Slice of Life' videodisc,  Keyboard Pathology Series,  Keyboard Publishing, Inc., 1990.

135. Trelstad RL (editor), 'Pathology  QuizBank, a hypertext bank of pathology questions, Keyboard  Pathology Series,  Keyboard Publishing, Inc., 1990.

136. Iyama KI, Ninomiya Y, Olsen, BR, Linsenmayer TF, Trelstad RL, Hayashi M. Spatio-temporal  pattern  of type X collagen gene expression and collagen deposition in embryonic chick vertebrae  undergoing endochondral ossification. Anat Rec 229:462-472, 1991.

137. Birk DE, Silver FH, Trelstad RL. Matrix Assembly  In: 'Cell Biology of Extracellular Matrix', Hay  ED, ed. Plenum Press, 1991, pp. 221-254.

138. Trelstad RL. The Nation's Medical Curriculum in Transition: Progression or Retrogression? (editorial).  Human Pathology 22:1183-1186, 1991.

139. Craighead JE, Trelstad RL. The Role of the Academic Pathologist in Environmental and Occupational Health Education. In: "Environmental and Occupational Disease" Universities Associated for  Research and Education in Pathology Monograph. Craighead, JE, ed., pp: 1-3, 1991.

140. Trelstad RL. The Fates of the New Properties: Intellectual Workproducts (editorial). Human  Pathology, 23: 89-90, 1992.

141. Hayashi M, Hayashi K, Iyama K, Trelstad RL, Linsenmayer TF, Mayne R. Notochord of chick  embryos secretes short-form type IX collagen prior to the onset of vertebral chondrogenesis. Developmental Dynamics. 194: 169-176, 1992.

142. Trelstad RL, Birk DE. Morphogenesis and Collagen Fibril Segments: Liquid Crystal Intermediates at  the Matrix-Cell Interface. In: ‘Dynamic Phenomena at Interfaces, Surfaces and Membranes’ Beysens  D, Boccara N, Forgacs G (eds). Nova Science Publishers, Inc., 1992, pp 11-21.

143. Trelstad RL, Raskova J. Teaching pathology without lectures through computer-based exercises,  small-group discussion and reading. Proc. Ann Sym on Computer App in Med Care: 781-782, 1993

144. Trelstad RL and Kemp PD. Matrix Glycoproteins and Proteoglycans. In: "Arthritis Surgery" Sledge CB, Ruddy S, Harris ED Jr., Kelley WN(eds)., WB Saunders Co, New York, 1994,  pp 48-70.

145. Trelstad RL, Martin EG, Shea SM, Raskova J. Information management technologies and their  emerging impact on learning pathology. In: "New Technologies in Pathology", Trump B, ed. 1994.

146. Kemp PJ, Trelstad RL. Matrix-Cell Molecular Biology. Digital Textbook Series, Keyboard Publishing,  Blue Bell, Pa., 1994.

147. Foran DJ, Goodell, LA, Trelstad, RL. A distributed system for remote consultation and medical education. IEEE Transactions in Medicine and Biology, 2: 1414-1416, 1994.

148. Trelstad RL and Godyn, JY (eds), 'Pathology VideoIndex 2', a hypertext guide to the 'Slice of Life VI' videodisc, Keyboard Pathology Series,  Keyboard Publishing, Inc., 1995.

149. Amenta PS, Martinez A, Trelstad RL. 'Repair and Regeneration.' In: "Anderson’s Pathology", Tenth Edition, Damjanov I and  Linder J (eds)., CV Mosby, Philadelphia, pp 416-447, 1996.

150. Raskova J, Trelstad RL. Replacing Lectures with Reading, Small Group Discussion and Computer  Assisted Learning: Results after Nine Years. Academic Medicine, 71:537-538, 1996.  

151. Trelstad RL, Amenta PS, Foran DJ, Smilow, PC. The Role for Regional Autopsy Centers in the Evaluation of Covered Deaths: Survey of Opinions of U.S. and Canadian Chairs of Pathology and Major Health Insurers in the United States. Arch Path Lab Med, 120:753-758, 1996.

152. Foran DJ, Winkelmann DA, Goodell LA, Trelstad RL. A Network-based Prototype for Interactive Telemedicine and Automated Management of Distributed, Clinical Databases. J Clinical Engineering. 25:383-391, 1996.  

153. Foran DJ , Meer P,  Papathomas TV,  Gong L, Kulikowski CA, Marsic I, Trelstad RL. Assessment of Subjective Criteria for Image Compression in Diagnostic Telepathology.  Proc. IEEE International Conference on Image Processing. 1: 873-878, 1996.

154. Sawai T, Uzuki M, Harris ED Jr, Kurkinen M, Trelstad RL,Hayashi M. In situ hybridization of stromelysin mRNA in the synovial biopsies from rheumatoid arthritis. Tohoku J. Exp. Med.178, 315-330, 1996.

155. Trelstad RL. Matrix Glycoproteins and Proteoglycans. In: Arthritis Surgery. Sledge CB, Ruddy S, Harris ED Jr, Kelley WN (eds)., WB Saunders Co, New York  pp 37-54, 1997.

156. Birk DE, Zycband EI, Woodruff S, Winkelmann DA, Trelstad RL.  Collagen fibrillogenesis in situ: Fibril segments become long fibrils as the developing tendon matures. Developmental Dynamics 208: 291-298, 1997.

157. Trelstad RL. Cell-Matrix Relationships are Dynamic and Regulatory. In: Anesthesia: Biologic Foundations. Yaksh TL, Maze M, Lynch C, Biebuyck JF, Zapol WM, Saidman LJ (eds)., Lippincott-Raven Press, Philadelphia, pp  1303-17, 1997

158. Trelstad RL. Editorial on 'Hospital Preparedness for Biological and Chemical Terrorism in Central New Jersey'. New Jersey Medicine, 98: 8, 2001

159. Maressa VA, Trelstad RL, Costante PA, Hirsch PJ. Interview of Professor Uwe E. Reinhardt. New Jersey Medicine 98:13-19, 2001