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Dong-Hua Yang, M.D., Ph.D.
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Position: Instructor of Pathology and Laboratory Medicine, Robert Wood Johnson
Medical School,
Administrative:
Department: Pathology and Laboratory Medicine
Lab Url:
Phone Number:
Fax Number:
Email
Address:
yangdo@umdnj.edu |
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Clinical and Research
Interests |
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Training |
 | Sun
Yat-Sen University of Medical Sciences, GuangZhou, China, 1981-7, BS
(equivalent) (Certified Medical doctor) |
 | Sun
Yat-Sen University of Medical Sciences, GuangZhou, China, 1981-7, MS
(equivalent) (Physiology) |
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Postgraduate School, Kagoshima University Faculty of Medicine,
Kagoshima, Japan, 1993-7, Ph.D. (equivalent) (Cell biology)
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Honors and Awards |
1996 Junior Investigator award, the 10th
International Congress of Histochemistry and Cytochemistry, Kyoto, Japan
1998
Vector Laboratories Young Investigator award, the 5th Joint Meeting
(United States & Japan), San Diego, USA
1998
International exchange award, The 12th Research Exchange, Ichiro
Kanehara Foundation, Tokyo, Japan
1999
MD Award - Soroptimist International of Kagoshima, Japan
1999
Section chair, 2nd Asian Pacific International Congress of Anatomists,
Beijing, China
2001
Honorable Mention award, Sixth Annual Postdoctoral Research Conference,
Fox Chase Cancer Center, Philadelphia, USA
2002
Gordon Research Conference (Mammalian Gametogenesis and embryogenesis)
Invited Speaker Travel Award, Connecticut, USA
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Certifications |
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Licensure |
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N.A. |
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Office Address |
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Mailing Address |
Department of
Pathology & Laboratory Medicine
675 Hoes Lane
UMDNJ - Robert Wood Johnson Medical School
Piscataway, NJ 08854, USA |
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Selected
Publications |
1. Yang D-H, I.H.
Roland, Andres Klein-Szanto and X.X. Xu The role of Disabled-2 in
epithelial polarity and tumorigenesis. Submitted for publication
2. Yang D-H, Z Fazili, E.R. Smith, , Q Cai, A. Klein-Szanto, C.
Cohen, IR Horowitz and X.X.Xu Disabled-2 heterozygous mice are
predisposed to endometrial and ovarian tumorigenesis and exhibit
sex-biased embryonic lethality in a p53 null background. Am. J. Path.
2006, 169:258-267
3. Yang D-H and E. G. Moss Temporally regulated expression of
Lin-28 in diverse tissue of the developing mouse. Gene Expression
Pattern 2003, 3(6): 719-26.
4. Roland IH, Yang WL, Yang D-H , Daly MB, Ozols RF, Hamilton TC,
Lynch HT, Godwin AK and XX Xu Loss of surface and cyst epithelial
basement membranes and preneoplastic morphologic changes in prophylactic
oophorectomies. Cancer 2003 98 (12): 2607-23
5. Yang D-H, E.R. Smith, I.H. Roland, Z. Sheng, J.,He, W. D.
Martin, J. D. Kambeth, T.H. Hamiton and X.X. Xu Disabled-2 is essential
for endodermal cell positioning and structural formation during mouse
embryogenesis. Dev. Biol.2002, 251:27-44
6. Yang D-H, E.R. Smith, C. Cohen, C. Patriotis, A.K. Godwin, T.C.
Hamilton and X.X.Xu Molecular events associated with dysplastic
morphological transformation and initiation of ovarian tumorigenicity.
Cancer 2002, 94: 2380-2392
7. Capo-Chichi CD, Smith ER, Yang DH, Roland IH, Vanderveer L,
Cohen C, Hamilton TC, Godwin AK, Xu XX. Dynamic alterations of the
extracellular environment of ovarian surface epithelial cells in
premalignant transformation, tumorigenicity, and metastasis. Cancer.
2002; 95(8):1802-15.
8. Smedberg JL, Smith ER, Capo-Chichi CD, Frolov A, Yang DH,
Godwin AK, Xu XX. Ras/MAPK Pathway Confers Basement Membrane Dependence
upon Endoderm Differentiation of Embryonic Carcinoma Cells. J Biol Chem.
2002, 277(43):40911-40918.
9. Smith E.R., C.D. Capo-chichi, J. He, J.L. Smedberg, M. E. Rula,
D-H Yang, A.H.Prowse, A.K. Godwin, T.C. Hamilton and X.X.Xu
Disabled-2 mediates c-Fos suppression and the cell growth regulatory
activity of retinoic acid in embryonic carcinoma cells. J. Biol. Chem.
2001, 276: 32094-32100
10. Yang D-H, Tsuyama S and Murata F The expression of gastric
H-K-ATPase mRNA and protein in developing rat fundic gland. Histochem J
2001, 33: 159-166
11. Yang D-H, Tsuyama S, Hotta K, Katsuyama T and Murata F
Expression of N-acetylglucosamine residues in developing rat fundic
gland cells. Histochem J 2000, 32(3): 187-193
12. Murata F, Yang D-H, Tsuyama S and Ohmori J Parietal cells
studied by means of electron microscopy, lectin staining,
immunohistochemistry and in situ hybridization. Italian J. Anat. Embryo.
1999, 104 suppl.1: 484
13. Tsuyama S, Yang D-H, Ohmori J and Murata F Ultracytochemical
localization of gastric proton pump by high pressure frozen and freeze
substitution method. Italian J. Anat. Embryo. 1999, 104 suppl.1: 721
14. Yang D-H, Tsuyama S, Ohmori J and Murata F Sulfated
glycosaminoglycans of guinea pig neutrophils studied by means of
cationic colloidal gold. J Histochem Cytochem 1999, 47(7): 881-887
15. Yang D-H, Tsuyama S, Ohmori J, Hotta K, Katsuyama T and
Murata F Phenotypic immunostaining of mucus-secreting cells of foregut
origin. Acta Histochem Cytochem 1999 32(2): 135-140
16. Ohmori J, Nawa Y, Yang D-H, Tsuyama S and Murata F Keratan
sulfate glycosaminoglycans in murine eosinophil-specific granules. J
Histochem Cytochem 1999, 47(4): 481-488
17. Miyauchi M, Tsuyama S, Yang D-H, Ohmori J, Kato K, Nakayama
J, Katsuyama T and Murata F Ontogeny of the rat parietal cell: analysis
using anti-parietal cell antibody and transmission electron microscopy.
Acta Anat Nippon 1999, 74(2): 197-207
18. Yang D-H, Tsuyama S, Ohmori J and Murata F Sulfated
glycosaminoglycans of guinea pig eosinophils studied by means of
cationic colloidal gold. Histochem J. 1998,30: 687-692
19. Yang D-H, Tsuyama S, Ohmori J and Murata F Sulfated
glycosaminoglycans of guinea pig basophils studied by means of cationic
colloidal gold. Histochem Cell Biol. 1998, 109: 189-194
20. Ge Y-B, Ohmori J, Tsuyama S, Yang D-H, Kato K, Miyauchi M and
Murata F Immunocytochemistry and in situ hybridization studies of
pepsinogen C producing cells in developing rat fundic gland. Cell Tiss.
Res. 1998, 293: 121-131
21. Yang D-H, Tsuyama S, Ge Y-B, Ohmori J, Wakamatsu D and Murata
F Proliferation and migration kinetics of stem cells in the rat fundic
gland. Histol. Histopath. 1997, 12: 717-728
22. Ge Y-B, Yang D-H, Ohmori J, Tsuyama S, Kim B-S, Kim J-B and
Murata F Cationic colloidal gold staining of acidic glycoconjugates in
mouse Paneth cells. Arch Histol Cytol 1997, 60: 133-142
23. Ohmori J, Tomita M, Nawa Y, Ge Y-B, Yang D-H, Tsuyama S and
Murata F Eosinophil peroxidase deficiency in human and mice. Acta
Histochem Cytochem 1997, 30: 231-236
24. Yang D-H, Kasamo H, Miyauchi M, Tsuyama S, and Murata F
Ontogeny of sulfated glycoconjugate producing cells in the rat fundic
gland. Histochem J 1996, 28:33-43
25. Kasamo H, Yang D-H, Tsuyama S, Ge Y-B and Murata F Ontogeny
of proliferative cells in the rat fundic gland. Acta Anat Nippon 1996,
71: 20-29
26. Zen Z-L, Wang Z-X, Yang D-H and Murata F Observation of
lectin binding sites in human fetal esophageal epithelium. Guangdong
Anatomical Bulletin 1995, 17: 47-49
27. Tsuyama S, Yang D-H, Kanae T, Kasamo H and Murata F
Immunoelectron microscopic labeling of digestive tract stem cells by
means of BrdU antibody. Acta Histochem Cytochem 1994, 27: 339-345
28. Murata F, Tsuyama S, Kanae T, Ihida K and Yang D-H Sites of
glycosylation observed by post-embedding and pre-embedding lectin
staining. Acta Histochem Cytochem 1994, 27: 607-612
29. Yang D-H The characteristics of lipolytic activity of
Staphylococcus Aureus on various agar culture. Food Inspec. Techniq.
1992, 3: 29-30
30. Yao YZ and Yang D-H Life cycle of membranous receptors. Prog.
Physiol. Sci. 1990, 21(3): 242-246
31. Yang D-H Transportation of intraventricular amines and its
possible mechanism. Proccedings of Sun Yat-Sen University of Medical
Sciences. 1990, 139-145
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Postdoctoral Position Available |
None
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Research Positions Available |
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None
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