UMDNJ - ROBERT WOOD JOHNSON MEDICAL SCHOOL
DEPARTMENT OF PATHOLOGY AND LABORATORY MEDICINE

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  Faculty Information

Peter S. Amenta, M.D., Ph.D.

Position: Professor and Chairman, Department of Pathology and Laboratory Medicine

Administrative: Interim Dean, UMDNJ - Robert Wood Johnson Medical School

Director, Immunohistochemistry Shared Resource, The Cancer Institute of New Jersey

Chief, Pathology Service, RWJUH 

Department: Pathology and Laboratory Medicine

Phone Number:
(732) 235-8120

Fax Number: (732) 235-8124

Email Address: amenta@umdnj.edu

Clinical and Research Interests
 

Electron microscopy

 

Training

bullet Trinity College, Hartford, CT,  B.S.
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Hahnemann University, Philadelphia, PA, M.D., 1980

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Hahnemann University,  Philadelphia, PA, Ph.D., 1984
Anatomic and Clinical Pathology Residency
, 1984

Honors and Awards

1979               Alpha Omega Alpha
1980               Hahnemann Club Award
1980               Honors in Anatomy
1980               Pediatrics Academic Recognition
1995, 1996       Gallo Award, The Annual Retreat on Cancer Research in New Jersey
1999               Gallo Award
           

 
Certifications Licensure

National Board of Medical Examiners, 1981

Anatomic & Clinical Pathology - American Board of Pathology, 1984

  New Jersey license

Pennsylvania license
     
Office Address   Mailing Address
Department of Pathology & Laboratory Medicine
MEB 212
UMDNJ - Robert Wood Johnson Medical School
New Brunswick, NJ 08903, USA
 
same
 
Selected Publications

1. Amenta, P.S., Gonick, P. and Katz, S. Testicular Sarcoidosis. Urology, 17:616-617, 1981.  

2. Amenta, P.S. and Katz, S.M.: Platelets in renal scleroderma. Arch. Path. Lab Med. 107:439-440, 1983.  

3. Amenta, P.S., Stead, J. and Kricun, M.: Cryptococcal Osteomyelitis. Skeletal Radiology. 9:263-265, 1983. 

4. Damjanov, I., Amenta, P.S. and Bosman, F.T.: Undifferentiated carcinoma of the colon containing exocrine, neuroendocrine and squamous cells. Virchows Arch. (Pathol. Anatomy), 401:57-66,1983. 

5. Amenta, P.S., Clark, C.C. and Martinez-Hernandez, A.: Depostion of fibronectin and laminin in the basement membrane of the rat parietal yolk sac: Immunohisto-chemical and biosynthetic studies. J. Cell Biol. 96:104-111, 1983. 

6. Martinez, A. and Amenta, P.S.: The basement membrane in pathology. Lab Invest. 48:656-677, 1983. 

7. Amenta, P.S.  in Histology and Embryology Review, 2nd Edition, ed. Peter S. Amenta, Ph.D., ARCO Publishing Co., 1983. 

8. Amenta, P.S.  in Histology, 3rd Edition, Peter S. Amenta, Ph.D., Medical Examination Publishing Co., The Digestive System. 1983.  

9. Damjanov, I., Amenta, P.S. and Zarghami, F.: Transformation of an AFP-positive yolk sac carcinoma to an AFP-negative neoplasm. Cancer, 53:1902-1907, 1984. 

10. Amenta, P.S., Vaheri, S., Gay, S. and Martinez-Hernandez, A.: The extracellular matrix of the human term placenta: Ultrastructural localization of collagen types I, III, IV, VI, fibronectin and laminin. Collagen Rel. Res. 6:125-152, 1986. 

11. Amenta, P.S. in Histology and Human Microanatomy, 5th edition, Peter S. Amenta, Ph.D., editor. The Digestive System, 1987. 

12. Amenta, P.S. and Martinez-Hernandez, A.: Specific methods for electron immunohistochemistry. Methods of Enzymology, 145:133-148, 1987.  

13. Haverty, T.P., Kelly, C., Hines, W.H., Amenta, P.S., Watanabe, M., Harper, R.A., Kefalides, N.A., and Neilson, E.G.: Characterization of a renal tubular cell line which secretes the autologous target antigen of autoimmune experimental interstitial nephritis. J. Cell Biol. 107:1359-1368, 1988. 

14. Karkavelas, G., Kefalides, N.A., Amenta, P.S. and Martinez-Hernandez, A.: Comparative ultrastructural localization of collagen types III, IV, VI and laminin in rat uterus and kidney. J. Molec. Ultrastr. Res. 100:137-156, 1988. 

15. Amenta, P.S., Gil, J. and Martinez-Hernandez A.: The connective tissue of the rat lung. II: ultrastructural localization of collagen types III, IV, and VI. J. Histochem. Cytochem. 36:1167-1173, 1988. 

16. Martinez-Hernandez, A. and Amenta, P.S.: Electron immunohistochemistry of the pulmonary extracellular matrix. in Lung Biology in Health and Disease: Models of Lung Disease: Microscopy and Structural Methods. Vol. 47. ed. Gil, J. and Lenfant, C. Marcel Dekker, Inc., New York. P.101-145, 1989. 

17. Bartnik, J., Powell, S., Katz, S.K. and Amenta, P.S.: Metaplastic Papillary Tumor of the Fallopian Tube: Case Report, Immunohistochemistry, and Review of Literature. Arch Path Lab Med. 113:545-547, 1988. 

18. Amenta, P.S. and Amenta, P.S., The Anatomy of the Spleen. in The Spleen: Structure, Function, and Clinical Significance. editor, Bowdler, A.J. Chapman & Hall, London, p. 1-7, 1989.  

19. Schwartz, D., Amenta, P.S. and Finkelstein, S.:Cerebral Pseudoallescheria Boydii infection: Unique occurrence of fungus ball (fungoma) in the brain. Clin. Neurol and Neurosurgery. 91:83-88, 1989. 

20. Glick, S., Teplick, S.K., and Amenta, P.S.: Microscopic (collagenous) colitis.  Am. J. Roentgenology 153:995-996, 1989. 

21. Amenta, P.S., Swartz, C. and Katz, S.M.: Concurrent focal segmental glomerulosclerosis and membranous nephropathy. Clinical Nephrology, 32:173-177, 1989. 

22. Amenta, P.S.  in Histology, 4th Edition, Peter S. Amenta, Ph.D., Medical Examination Publishing Co., Chapter 17 -The Digestive System. 1990. 

23. Glick, S.N., Teplick, S.K., and Amenta, P.S.: Giant hyperplastic polyps of the gastric remnant, simulating primary gastric stump cancer. Gastrointestinal Rad. 15:151-154, 1990. 

24. Kelch, B.P., Bulova, S.I., Crilley, P., Topolsky, D. and Amenta, P.S.: An unusual extramedullary relapse of acute myelogenous leukemia after allogeneic bone marrow transplantation. Am. J. Clin. Oncology. 13:238-243, 1990. 

25. Weisman, D., Amenta, P.S., and Kantor, G.: Vulvar epithelioid sarcoma metastatic to the scalp. A case report and review of the literature. Am J Dermatopath. 12:462468, 1990.

26. Martinez-Hernandez, A. and Amenta, P.S.: Basic concepts in wound healing. In Sports-Induced Inflammation: Clinical and Basic Science Concepts. Eds. Leadbetter, W.B., Buckwalter, J.A., and Gordon, S.L.  American Academy of Orthopedic Surgeons, IL. pp. 55-101, 1990. 

27. Martinez-Hernandez, A.M., Martinez-Delgado F., and Amenta, P.S.: The  extracellular matrix in hepatic regeneration. Localization of collagen types I, III IV, laminin and fibronectin. Lab. Invest. 64:157-166, 1990.  

28. Deak, S.B., Glaug, M.R., Pierce, R.A., Bancila, E., Friedman, J., Amenta, P.S., Mackenzie, J.W., Greco, R.S., and Boyd, C.D.: Desmoplasia in benign and malignant breast disease is characterized by alterations in level of mRNAs coding for types I and III procollagen. Matrix, Collagen and Related Research. 11:252-258, 1991. 

29. Barrone, J., Cummings, K., Smilow, P., and Amenta, P.S.: Granulomatous prostatitis. Infections in Urology. 4:69-71, 1991. 

30. Gunnia, U., Amenta, P.S., Seibold, J.R., and Thomas, T.J.: Inhibition of ornithine decarboxylase (ODC) activity in MRL-lpr/lpr mice: Effects on renal histology. Kid. Int. 39:882-890, 1991. 

31. Deak, S.B., Scholz, P.M., Amenta, P.S., Constantinou, C. D., Levi-Minzi, S. A., Gonzalez-Levin, L., and Mackenzie, J.W.: The substitution of arginine for glycine85 of the alpha 1(I) procollagen chain results in mild osteogenesis imperfecta: The mutation provides direct evidence for three discrete domains of cooperative melting of intact type I collagen. J. Biol. Chem. 266:21827-21832, 1991. 

32. Baloch, Z., Klapper, J., Buchanon, L., Schwartz, M. and Amenta, P.S.: Ontogenesis of the murine hepatic extracellular matrix: An immunohistochemical study. Differentiation 51:209-218,1992. 

33. Mack, R.B., Katz, S.M., and Amenta, P.S.: Choriocarcinoma of the kidney: Case report and review of literature. JAOA. 92:799-802, 1992. 

34. Maiese, S., Amenta, P.S., and Spence, M.: Endometriosis following hysterectomy and oophorectomy: A case report. Am. J Gynecol. Health. 6:22-25, 1992.  

35. Giannakopoulus, G., Nair, S., McCormack, T.M., and Amenta, P.S.:  Implications for the pathogenesis of aneurysm formation: Metastatic choriocarcinoma with spontaneous splenic rupture. Case report and a review. Surg. Neurol. 38:236-240, 1992.  

36. Gaur, S., Cappell, M.S., Dadhania, J., Lupski, D., Mascarhenas, M., Amenta, P.S., Bharucha, N., and Rosenthal, S. Cholestatic giant cell hepatitis associated with ultrastructural evidence of intrahepatic retroviral infection in a human immunodeficiency virus seropositive infant. J Ped Gastroenterol Nutri. 16:199-202, 1993. 

37. Martinez-Hernandez, A. and Amenta, P.S.: Morphology, localization and origin of the hepatic extracellular matrix. in The Extracellular Matrix and Liver Disease. eds. Zern, M. A. and Reid, L. Marcel Dekker, Inc., New York. p.255-327, 1993. 

38. Martinez-Hernandez, A. and Amenta, P.S.: The hepatic extracellular matrix. I. Components and distribution in normal liver. Virchows Arch (Pathol. Anatomy) 423:1-11, 1993. 

39. Martinez-Hernandez, A. and Amenta, P.S.: The hepatic extracellular matrix. II. Ontogenesis, regeneration, and cirrhosis. Virchows Arch (Pathol. Anatomy) 423:77-84,1993. 

40. Das, K., Prasad, I., Garla, S., and Amenta, P.S.: Immunocytochemical detection of Barrett's Epithelium using a novel monoclonal antibody. Ann Int Med 120:753-756, 1994. 

41. Amenta, P.S. and Martinez-Hernandez, A.: Immunological approaches to the identification of extracellular matrix components in tissues and cell cultures. In: Extracellular Matrix: A Practical Approach. Eds. Haralson, M.A. and Hassell, J.R. IRL Press. Oxford. Chapter 14, pp. 303-327, 1995. 

42. Sutkawski, N., Kuo, M-L., Amenta, P.S., Dougherty, J.P., Ron, Y. A peripheral blood-derived monolayer supports long-term cultures of CD4+ and CD8+ T lymphocytes. Circ. Res. 85:3213-3222, 1995. 

43. Martinez-Hernandez, A. and Amenta, P.S.: The extracellular matrix in hepatic regeneration. FASEB J  9:1401-1410, 1995. 

44. Sechler, J.L., Sandberg, L.B., Roos, P.J., Snyder I., Amenta, P.S., Riley, D.J., and Boyd, C.D.: Elastin gene mutations in transgenic mice. Ciba Found Symp. 192:148-165, 1995. 

45. Drachtman, R.A., O'Connor, O.A., Amenta, P.S. and Ettinger, L.J.: Successful treatment of an infant with an undifferentiated primary cardiac sarcoma.  J. Ped. Hem. Onc. 1996 18:314-317, 1996. 

46. Trelstad, RL, Amenta, P.S., Foran, DJ, and Smilow, PS: The role for a regional autopsy centers in the evaluation of covered deaths: Survey of opinions of U.S. and    Canadian chairs of Pathology and major health insurers in the United States. Arch. Path. Lab. Med. 120:753-758, 1996.

47. Pantuck, A.J., Barone, JG, Amenta, P.S., Smilow, P.S. and Cummings K.B.:      Diagnosis and management of malignant perirenal schwannoma. Am. Surgeon.   62:1024-1027, 1996. 

48.Myers, J.C., Dion, A.S., Abraham, V., Amenta, P.S.: Type XV collagen exhibits a   widespread distribution in human tissues but a distinct localization in basement        membrane zones Cell and Tissue Res. 286:493-505, 1996. 

49. Sechler, J.L., Cardone, J.C., Alatawi, A., Friedman, J., Amenta, P.S., Bancila, E., Tozzi, C.A., Pierce, R.A., Deak, S.B., and Boyd, C.D.: Altered tropoelastin gene expression is associated with the development of hypertension in the spontaneously hypertensive (SHR) rat. Connective Tissue Res 286:493-505, 1996. 

50.  Wapnir, I.L., Southard, H, Chen, G., Friedman, J. Boyd, C., and Amenta, P.S. Collagen gene expression in the neomatrix of carcinoma of the breast. Invasion and Metastasis. 16:308-316, 1996. 

51. Martinez-Hernadez, A., Trelstad, R., and Amenta, P.S. Repair and regeneration in Anderson's Pathology 10th edition , Damjanov, I. and Linder, J. eds. Chapter 19. p. 416, 1996. 

52. Amenta, P.S. and Harrison, D.: The distribution and potential role in the extracellular matrix in hepatic ontogenesis: A review. Micros. Res. Tech. 39:372-386, 1997. 

53. Myers, J.C., Li, D., Bageris, A., Abraham, V., Dion, A.S. and Amenta, P.S. Biochemical and immunohistochemical characterization of human type XIX collagen defines a novel class of basement membrane zone collagens. Am. J. Pathol. 151:1729-1739, 1997. 

54. Pantuck, A.J., Bancila, E., Das, K. M., Amenta, P.S., Cummings K.B., Marks, M. and Weiss, R.: Adenocarcinoma of the urachus and bladder expresses a unique colonic epithelial epitope: An immunohistochemical study. J. Urology  158:1722-1727, 1997.  

55. Amenta P.S, and Amenta, P.S. ed. Histology: From Human Microanatomy to Pathology.  Seventh edition. Piccin, Padova Italy 1997. 

56. Hock, D.L., Amenta, P.S. and Kemmann, E.: Is the endometrial suction curette useful in the detection of chorionic villi during the first trimester? Biology and Medicine 3: 225-227, 1997. 

57. Sullivan, G., Amenta, P.S., Villanueva, J.D., Alvares, C.J., Yang, J-M., and Hait, W.N. The expression of drug resistance gene products during the progression of human prostate cancer. Clin. Can. Res. 4:1393-1403, 1998. 

58. Griffel, L.H., Baron-Gabriel, I., Amenta, P.S., and Das, K.M.: What precisions can be made on differences between Barrett’s epithelium and intestinal metaplasia by immunocytochemistry?  The role of a novel marker.  In Giuli R, Galmiche J-P, Jamieson GG, and Scarpignato C., Editors.  The Esophagogastric Junction: 420 questions, 420 answers.  Pp. 976-978. John Libbey Eurotext, Paris, 1998. 

59. Pantuck, A., Bancila, E., Amenta, P.S., Cummings, K. and Weiss, R. The monoclonal antibody 7E12H12 can differentiate primary adenocarcinoma of the bladder and prostate. British J. Urol. 82:426-430, 1998. 

60. Murphy, D.M. Pantuck, A.J., Amenta, P.S., Das, K.S., Cummings, K.B., Keeney, G. L., Weiss, R.E. Female urethral adenocarcinoma: Immunohistochemical evidence for more than one tissue of origin. J. Urol. 161:1881-1884, 1999. 

61. Shah, P.C., Brolin, R.E. Amenta, P.S., and Deshmukh, D.R.  Effect of aging on intestinal ischemia and reperfusion injury. Mechanisms of Aging and Development, 107:37-50, 1999. 

62. Shah, N., Antony, T., Hadad, S., Amenta, P.S., Shirahata, Thomas, T.J., and Thomas, T.  Antitumor effects of Bis(ethyl)polyamine analogs on mammary tumor development in FVB/N-TgN (MMTV-neu) transgenic mice. Can. Let. 146:15-23, 1999. 

63. Balabhadrapathruni, S., Thomas, T,J., Yurkow, E.J., Amenta, P.S., and Thomas, T. Effects of Genestin and structurally related phytoestrogens on cell cylce kinetics and apoptosis in MDA-MB-468 human breast cancer cells. Oncology Reports 7: 3-12, 2000.

64. Griffel, L.H., Amenta, P.S., Das, K.M.: Use of a novel monoclonal antibody in diagnosis of barrett’s esophagus. Digestive Diseases and Sciences. 45:40-48, 2000.

65. Amenta, P.S., Briggs, K., Xu, K., Gamboa, E., Jukkola, A.F., Li,  D., Myers, J.C. Type XV collagen in human colonic adenocarcinomas has a different tissue distribution than other basement membrane zone proteins. Human Pathology 31:359-366, 2000. 

66. Ettinger, L.J., Goodell, L., Javidian, P., Hsieh, Y. Amenta, P.S.: Long-term survival in an adolescent with widely metastatic renal cell carcinoma with rhabdoid features. J Ped. Hem/Onc. 22:173-175, 2000.

67. Tazebay, U.H., Wapnir, I.L., Levy, O., Dohan, O. Zuckier, L.S., Zhao, Q.H., Deng, H.F., Amenta, P.S. Fineberg, S. Pestell, R.G., and Carrasco, N.: The mammary gland iodide transporter is expressed during lactation and in breast cancer. Nature Medicine, 6:871-878, 2000. 

68. Onuma, E. K., Amenta, P.S., Ramaswamy, K., Lin, J. J.-C., Das, K. M. Autoimmunity in ulcerative colitis (UC): a predominant colonic mucosal B cell response against human tropomyosin isoform 5. Clin Exp. Immunol. 121:466-471, 2000. 

69. Griffel, L.H., Amenta, P.S., and Das, K.M. Use of a monoclonal antibody in the diagnosis of Barrett’s Esophagus. Digestive Diseases and Sciences 45:40-48, 2000. 

70. Onuma, E.K., Amenta, P.S., Jukkola, A.F., Mohan, V., Borra, S., Das, K.M. A phenotypic change of small intestinal epithelium to that of colonocytes in small intestinal adenomas and adenocarcinomas. American Journal of Gastroenterology 96:2480-2485,2001.  

71. Dasgupta, A. Ramaswamy,K., Giraldo, J. Taniguchi, M. Amenta, P.S., Das, K.M.  Colon Epithelial Cellular Protein Induces Oral Tolerance in the Experimental Model of Colitis by Trinitrobenzene Sulfonic Acid.  Journal of Laboratory and Clinical Medicine. 138:257-269, 2001  

72. Dasgupta, A., Kesari, K.V., Ramaswamy, K.K., Amenta, P.S., Das, K.M. Oral      Administration of Unmodified Colonic but not Small Intestinal Antigens Protects Rats for Hapten-induced Colitis. Clinical and Experimental Immunology.  125:41-47, 2001  

73. DiPaola, R. S., Chenven, E.S., Shih, W.J., Lin, Y., Amenta, P.S., Goodin, S.        Shumate, A,, Cappanna, T., Cardiella, M., Cummings, K.B., Aisner, J., Todd, M.B.  Mitoxantrone in patients with prostate specific antigen progression after local   therapy for prostate cancer. Cancer 92:2065-2071                                                   

74. Suh, J.S., Payvandi, F. Edelstein, L.C., Amenta, P.S., Zong, W-X, Gelinas, C., Rabson, A.B. Mechanisms of Constitutive NF-kB Activation in Human Prostate Cancer Cells.  The Prostate 52:183-200,2002  

75. Lin, J.L.-C., Geng, X., Das-Bhattacharya, S., Yu, J-R., Reiter, R.S., Sastri, BN., Glazier, K.D., Mirza, Z.K., Wang, K.K., Amenta, P.S., Das, K.M., Lin, J.J-C. Isolation and sequencing of the novel tropomyosin isoform preferentially associated with colon cancer. Gastroenterology 123:152-162,2002  

76. Wolf, C., Seldernrijk, A.S., Das, D.M., Timmer, R., Breumelhop, R., Smout,  A.J.P.M., Amenta, P.S., Griffel, L.H.  Prevalence of mAbDAS-1 in biopsy specimens from the esophagogastric junction.  Am J Gastroenterol  97:2979-2985, 2002 

77. Mirza, A.K., Amenta, P.S., Griffel, L. H., Ramsundar, L. Slate, J. Prasad, S. Yokota, K. Tanabe, H., Sato, T., Kohgo, Y., Das, K.M. Gut. Gastric intestinal metaplasia as detected by a novel biomarker is highly associated with gastric adenocarcinoma. 52:807-812, 2003.

78. Amenta, P.S., Lee, M.T., Hadad, S., Barnard, N.,  Li,  D., Myers, J.C. Loss of types XV and XIX collagen precedes basement membrane invasion in ductal carcinoma of the female breast. J Path, 199:298-308, 2003.

79. Wapnir, I.L., van de Rijn, M., Nowels, K., Amenta, P.S., Walton, K., Montgomery,  K., Greco, R.S., Dohan, O., Carrasco, N. Immunohistochemical Profile of the Sodium/Iodide Symporter (NIS) in Thyroid, Breast and Other Carcinomas Using High Density Tissue Microarrays and Conventional Sections. J Clin Endocrinol Metab. 88:1880-1888, 2003.

80. Myers, J.C., S., Li,  D., Amenta, P.S., Clark, C.C., Nagaswami, C. Weisel, JW. Type XIX collagen purified from human umbilical cord is characterized by multiple sharp kinks delineating collagenous subdomains and by intermolecular aggregates via globular disulfide-linked and heparin-binding amino termini. JBC 278:32047-32057, 2003.

81. Langenfeld, E.M., Calvano, S.E., Lowry, S.F., Amenta, P.S.,  Langenfeld, E.M., The mature bone morphogenetic protein-2 is aberrantly expressed in non-small cell lung carcinomas and stimulates tumor growth of A549 cells. Carcinogenesis 24:1445-1454, 2003

82. Yurchenco, P.D., Amenta, P.S., Patton, B. Basement membrane assembly and stability seen through a developmental lens. Matrix Biology 22:521-538, 2004.

83.  Perrotti, M., Ankem, M., Bancila, E., deCarvalho, V., Amenta, P.S., Weiss, R.J.urolonc 22: 174-177,2004.

84. Amenta, P.S., Scivoletti, N., Newman, M., Sciancalepore, J., Li, D., Myers, J. C. Proteoglycan-Collagen XV Tissues is Seen Linking Banded Collagen Fibers Subjacent to the Basement Membrane. J.Histochem Cytochem 53:165-176, 2005.

 

 

 

Postdoctoral Position Available
None
 
Biographical Listings

1978, 1982         Who's Who in American Colleges and Universities
1996                 Who's Who in American Science and Engineering

1997                 Who's Who in America in Medicine and Healthcare

1998                 Top Doctors in New Jersey
1998                 Best Doctors in America
 

Updated Date
09/20/2002

 

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