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Billie S. Fyfe-Kirschner, MD
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Position:
Professor,
Department
of Pathology and Laboratory Medicine
Administrative:
Chief,
Division of Nephropathology -
Robert Wood
Johnson University Hospital (RWJUH)
Director of Autopsy Service,
Director of Transplant Pathology
Robert Wood Johnson University Hospital, New Brunswick, NJ,
Pathology Residency Program Director, Robert Wood Johnson Medical
School, New Brunswick, NJ
Department: Pathology and Laboratory Medicine
Phone Number:
(732) 235-8114
Email
Address:
fyfekibs@umdnj.edu |
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Training |
 | University of
Miami School of Medicine, Miami, Florida
Doctor of Medicine, (Combined B.S./M.D. Program), 1983-1987
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Residency in Anatomic
Pathology, Mount Sinai Medical Center
Miami Beach, Florida, 1987-1989
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Residency, Anatomic
Pathology, The Mount Sinai Medical Center
New York, New York, 1989-1990
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Fellowship, Anatomic Pathology,
The Mount Sinai Medical Center
New York, New York 1990-1991
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Visiting Fellowship, Cardiac
Pathology, Brigham and Women's Hospital Boston, MA, 1991
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Honors and Awards |
 | Member, Alpha Omega Alpha Medical Student Honor
Society, 1987
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 | Sidney Israel Resident in Pathology (Best
Resident Award)
Mount Sinai Medical Center, Miami Beach, Florida, 1988
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 | Best Resident Presentation in Pathology: Gastric
Syphilis: An entity forgotten too soon?
Southern Medical Association Meeting, 1989
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 | Young Investigator Award from the Society for
Cardiovascular Pathology for: Early Ischemic Injury in
Post-transplant Endomyocardial Biopsies: Morphology and Clinical
Significance, 1993
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Certifications |
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Licensure |
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Anatomic Pathology -
American Board of Pathology, 1991 |
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1990 New York State License
1995 Pennsylvania State License
2004 New Jersey State License
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Office Address |
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Mailing Address |
Department of
Pathology & Laboratory Medicine
One Robert Wood Johnson Place
Robert Wood Johnson University Hospital
New Brunswick, NJ 08901, USA |
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Selected
Publications |
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Fyfe B, Popitti RJ, Jr, Amazon
K, Razzetti A.. Intraosseous Echinoccosis: A rare manifestation of
echinococcal disease. Southern Medical Journal 83:211-215, 1990.
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Fyfe B, Dominquez F, Popitti RJ,
Jr.. Thymic Hyperplasia: A clue to the diagnosis of hyperthyroidism.
The American Journal of Forensic Medicine and Pathology 11: 257-261,
1990.
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Fyfe B, Mittleman R.
Hypopharyngeal lipoma as a cause of sudden death. American Journal
of Forensic Medicine and Pathology 12:82-84, 1991.
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Rafanti SP, Fyfe B, Carreiro S,
Sharp S, Hyma B, Ratzan K. Native valve endocarditis due to
Pseudallescheria Boydii in a patient with Acquired Immune Deficiency
(AIDS): A case report and literature review. Reviews of Infectious
Diseases 12:993-996, 1990.
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5. Marmur J, Rossikhina M,
Arabinda G, Fyfe B, Friedrich V, Mendlowitz M, Nemerson Y, and
Taubman M. Tissue Factor is rapidly induced in arterial smooth
muscle after balloon injury. Journal of Clinical Investigation
91:2253-2259, 1993.
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Fyfe B, Popitti RJ, Jr, Lubin J,
Robinson MJ. Gastric Syphilis: Primary diagnosis by gastric biopsy:
Report of four cases. Archives of Pathology and Laboratory Medicine
117:820-823, 1993.
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Fyfe B, Schoen FJ. Pathologic
analysis of 34 explanted Symbion ventricular assist devices and 10
explanted Jarvik-7 Total artificial hearts. Cardiovascular Pathology
2:187-198, 1993.
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Groisman G, Ben-Izhak O,
Schwerenz A, Berant N, Fyfe B. The value of polyclonal
carcinoembryonic antigen immunostaining in the diagnosis of
microvillous inclusion disease. Human Pathology 24: 1232-1237, 1993.
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Hytiroglou P, Dolgin S, Fyfe B,
Thiese N, Thung S, Toor A. Focal nodular hyperplasia in a 10 month
old infant. Letter to the editor, Pediatric Pathology 13:537-539,
1993.
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Pastores G, Santorelli F,
Shanske S, Gelb B, Fyfe B, Wolfe D, Willner J. Leigh syndrome and
hypertrophic cardiomyopathy in an infant with a mitochondrial point
mutation (T8993G). American Journal of Medical Genetics 50:265-271,
1994.
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Fyfe B, Quintana C, Kaneko M,
Griepp R. Aortic sarcoma four years after Dacron graft insertion.
Annals of Thoracic Surgery 58: 1752-1754, 1994.
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Fyfe B S, Israel DH, Quish A,
Squire A, Burrows L, Sharma S, Murthy S, Machac J. Reversal of
primary hyperoxaluria cardiomyopathy after combined liver and renal
transplantation. American Journal of Cardiology 75:210-212, 1995.
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Go L, Moschella M, Watras
J, Handa K, Fyfe BS, Marks AR. Differential regulation of two types
of intracellular calcium release channels during end stage heart
failure. Journal of Clinical Investigation 95: 888-894, 1995.
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Kirschner RE, Chiao JC, Fyfe BS,
Hoffman LA, Davis JM, Fantini GA. Neutrophil lipoxygenase activation
and leukosequestration in post-ischemic myocutaneous flaps: Role of
LTB4. American Journal of Physiology 268 (Heart Circ Physiol 37):
2167-2171, 1995.
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Fyfe B, Loh E, Winters G L,
Kartashov A, Couper G S, Kartashov A I, Schoen F J. Heart
transplantation-associated perioperative ischemic myocardial injury:
Morphological features and clinical significance. Circulation: 1996;
93:1133-1140.
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Schecter SO, Fyfe B, Pou R,
Goldman ME. Intramural left atrial hematoma complicating mitral
annular calcification. American Heart Journal 1996; 132: 455-457.
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Berkowitz J, Unger P, Fyfe B.
Sarcoidosis involving a paratesticular adenomatoid tumor.
Sarcoidosis Vasculitis and Diffuse Lung Diseases 1996; 13:183-185.
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Marmur JD, Thiruvikraman SV,
Fyfe BS, Guha A, Sharma SK, Ambrose JA, Fallon JT, Nemerson Y,
Taubman MB. Identification of Active Tissue Factor in Human Coronary
Atheroma. Circulation 1996; 94:1226-1232.
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Yokoyama H, Momeni R, Goldstein
C, Mohuiddin M, Shen Z, Fyfe BS, Whitman GJ, DiSesa VJ. Effects of
Vesnarinone, a Novel Orally Active Inotropic Agent with an
Immunosuppressive Action, on Experimental Cardiac Transplantation in
Rats. Transplantation 1996; 62:1540-3.
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Hague K, Catalano P, Rothschild
M, Strauchen J, Fyfe B. Posttransplant Lymphoproliferative Disease
Presenting as Sudden Respiratory Arrest in a Three-Year-Old Child.
Ann Otol Rhin and Laryngol 1997; 106: 244-247.
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Kirschner RE, Fyfe B, Hoffman
LA, Chiao JC, Davis JM and Fantini GA. Ischemia- reperfusion injury
of myocutaneous flaps: Role of leukocytes and leukotrienes. Plastic
and Reconstructive Surgery 1997; 6:1485-1493
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Taubman MT, Fallon JT, Schecter
AD, Giesen P, Mendlowitz M, Fyfe B, Marmur JD and Nemerson Y. Tissue
factor in the pathogenesis of atherosclerosis. Thrombosis and
Haemostasis 1997; 78:200-204.
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Schecter AD, Giesen PL, Taby O,
Rosenfield CL, Rossikhina M, Fyfe BS, Kohtz DS, Fallon JT, Nemerson
Y, Taubman MB. Tissue Factor Expression in Human Arterial Smooth
Muscle Cells. TF is Present in Three Cellular Pools AfterGrowth
Factor Stimulation. Journal of Clinical Investigation 1997; 100:
2276-2285.
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Berkowitz J., Lansman S.
and Fyfe B. Coronary Artery Mycotic Aneurysm Following Endocarditis
of Composite Graft. Angiology 1998; 49: 145-150.
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Fyfe B, Garcia FU. Laryngeal
glycogenic acanthosis presenting as leukoplakia. Archives of
Otolaryngology and Head and Neck Surgery 1998; 124: 1029-1030.
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Sicari MC, Fyfe B, Parness
I,Rossi A, Unger P. Intrapericardial yolk sac tumor associated with
acute myocarditis. Archives of Pathology and Laboratory Medicine
1999; 123: 241-3.
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Kirschner RE, Xu J, Fyfe B,
Chang B, Bucky LP. Salvage of free flaps after secondary venous
ischemia by local delivery of heparin. Annals of Plastic Surgery
1999; 42: 521-527.
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Fyfe B, Schoen FJ. Pathologic
analysis of non-stented Freestyle aortic root bioprostheses treated
with amino oleic acid (AOA). Seminars in Thoracic and Cardiovascular
Surgery 1999; Suppl I: 151-156.
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Giesen PLA, Fyfe BS, Fallon JT,
Roque M, Mendlowitz M, Rossikhina M, Guha A, Badimon JJ, Nemerson Y
and Taubman M. Intimal tissue factor activity is released from the
arterial wall after injury. Thrombosis and Haemostasis 2000; 83:
622-628.
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Samuels LE, Thomas MP, Holmes
EC, Narula J, Fitzpatrick J, Wood D, Fyfe B, Wechsler AS.
Insufficiency of the native aortic valve and left ventricular assist
system inflow after support with an implantable left ventricular
assist system: signs, symptoms, and concerns. J Thor Cardiovasc Surg
2001; 122: 380-381.
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Narula J, Acio ER, Narula
N, Samuels LE, Fyfe B, Wood D, Fitzpatrick JM, Ragunath PN,
Tomaszewski JE, Kelly C, Steinmetz N, Green A, Tait JF, Leppo J,
Blankenberg FG, Jain D, Strauss HW. Annexin-V imaging for
non-invasive diagnosis of cardiac allograft rejection. Nat Med 2001;
12: 1347-52.
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Fasseas P, Galatro KM,
Leybishkis B, Fyfe B. Cardiac involvement in sarcoidosis. Tex Heart
Inst 2001; 28: 154-5.
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Leon ME, Chavez C, Fyfe B,
Nagorsky MJ, Garcia FU. Cholesterol granuloma of the maxillary
sinus. Arch Path Lab Med 2002; 126:217-219.
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Nissman SA, Mann BD, Vitvisky EV,
Fyfe BS. Spontaneous nontraumatic hemoperitoneum due to a bleeding
arteriovenous malformation on the serosal surface of the transverse
colon: a case report. American Surgeon 2002; 68:911-912.
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Kode R, Fa K, Chowdhury S,
Ranganna K, Fyfe B, Stabler S, Damask A, Laftavi M, Kumar AM,
Pankewycz O. Basiliximab plus low-dose cyclosporine vs. OKT3 for
induction immunosuppression following renal transplantation.
Clinical Transplantation 2003; 17: 369-376.
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Gabriel S, Gracele E,
Fyfe-Kirschner B. Impact of BMI on Clinically Unsuspected Findings
at Postmortem Examination. Accepted for Publication American Journal
of Clinical Pathology 2005.
Books and Chapters:
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Fyfe, B. Cardiovascular
Pathology pp 83-104.In: Pathology a Comprehensive Review. Klein MJ
and Heller D. Eds. Butterworth-Heinmann Publishers Newton, MA 1999
Workshops:
National:
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“Diagnostic and Practical
Challenges in Modern Autopsy Practice” ASCP Fall Meeting 1999, New
Orleans, LA. Billie Fyfe, MD Course director.
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“Diagnostic and Practical
Challenges in Modern Autopsy Practice” ASCP Fall Meeting 2000, San
Diego, CA. Billie Fyfe, MD Course director.
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