UMDNJ - ROBERT WOOD JOHNSON MEDICAL SCHOOL
DEPARTMENT OF PATHOLOGY AND LABORATORY MEDICINE

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  Faculty Information

Tetsuo (Tetsuho)Shimamura, M.D., Ph.D.

Position:  Professor, Department of Pathology and Laboratory Medicine

Administrative:

Department: Pathology and Laboratory Medicine

Phone Number: (732) 235-5338

Fax Number: (732) 235-4825

Email Address: shimamte@umdnj.edu
Clinical Programs
 
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Diagnostic Nephropathology Service: UMG & RWJUH        
Research Interests
 
 Nephropathology
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   Mechanisms of progression of chronic renal diseases

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   Mechanisms of development of Interstitial nephritis

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   Genitourinary neoplasms

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   Nephrotoxicity of drugs

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   Cell adhesion molecules

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   Oxidants, genes, and renal diseases

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   Injury and Repair

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   Hypertensive Vascular Injury
 

Training
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Yokohama University, Sch. of Med., M.D., 1959

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Washington Univ., Sch. of Med., St. Louis, Mo., Residency Training in Anat. Path. US Public Health Trainee in Exp. Pathology, 1961-1964

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Methodist Hosp., Baylor Univ., Coll. of Med., Houston, Tex., Residency in Surg. Path., 1964-1965

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Yokohama University, Sch. of Med., Ph.D., 1988
 

Honors and Awards


1958       President, Medical Student Association, Yokohama City Univ., Sch. of Med.  1968       Golden Apple Award
1978       Award from NMSA, Rutgers Chapter
1979       Award from NMSA, Rutgers Chapter
 
Certifications Licensure

ECFMG, 1960

Anatomic & Clinical Pathology - American Board of Pathology, 1968

   New Jersey license: No. 26770
South Dakota license: No. 744
Japanese license:No. 173548

 
     
Office Address   Mailing Address
Department of Pathology & Laboratory Medicine
UMDNJ - Robert Wood Johnson Medical School
675 Hoes Lane
Piscataway, NJ 08854, USA
 		 same
 
Selected Publications

  1. T. Shimamura and R. H. Heptinstall. Experimental pyelonephritis: Nephron dissection of the kidney of experimental chronic pyelonephritis in the rabbit. J. Path. Bact. 85: 421-3, 1963.

  2. G. D. Sorensen and T. Shimamura. Experimental amyloidosis: III. Light and electron microscopic observations of renal glomeruli. Lab. Invest. 13: 1409-17, 1964.

  3. E. I. Karl, P. Garcia, W. L. White, L. Recant, and J. M. Kissane. Proteinuria induced by albumin injection. Lab. Invest. 13: 1600, 1964 (Acknowledgement).

  4. T. Shimamura and G. D. Sorensen. Experimental amyloidosis: V. Relationship beTween experimental glomerular amyloid and the mesangial region. Am. J. Path. 46: 645-56, 1965.

  5. T. Shimamura and G. D. Sorensen. Electron microscopy of serial sections of the murine glomerular mesangium. Anat. Rec. 152: 141-153, 1965.

  6. T. Shimamura, F. Gyoerkey, R. O. Morgen, and M. E. DeBakey. Fine structural observations in human kidney homografts. Invest. Urol. 3: 590-598, 1966.

  7. T. Shimamura, J. M. Kissane, and F. Gyoerkey. Experimental hydronephrosis: Nephron dissection and electron microscopy of the kidney following obstruction of the ureter and in recovery from obstruction. Lab. Invest. 15: 629-40, 1966.

  8. F. Gyoerkey and T. Shimamura. Virus-like particles observed in a human sweat gland carcinoma. Yoko. Med. Bull. 18: 1-3, 1967. 

  9. F. Gyoerkey. T. Shimamura, and R. M. O'Neal. The fine structure of ceroid in human atheroma. J. Histochem. Cytochem. 15: 732-36, 1967. 

  10. T. Shimamura and E. H. Shaw. Crystalline structure in juxtaglomerular granules of the rat. S. Dak. J. Med. 21: 33-5, 1968.

  11. T. Shimamura. Presence of juxtaglomerular cells away from the glomerular hilus in mouse. S. Dak. J. Med. 21: 49-51, 1968.

  12. T. Shimamura and E. Shaw. Glomerular basement membrane changes in experimentally-induced lathyrism in rats. S. Dak. J. Med. 21: 67-9, 1968.

  13. T. Shimamura, T. Kawakami, and A. C. Beall. Smooth muscle cells in replacement Teflon grafts. Minn. Med. 51: 779-81, 1968. 

  14. T. Shimamura. Studies on the aortic sclerosis and calcification in rats with experimentally induced chronic renal failure. Exp. Mole. Path. 13: 79-88, 1970. 

  15. T. Shimamura, F. Gyoerkey, T. Kawakami, A. C. Beall, and M. E. DeBakey. The ultrastructure of neointima of canine infrarenal vena caval Teflon prostheses. Exp. Mole. Path. 13: 190-8, 1970. 

  16. T. Shimamura. Renal medullary fibrosis associated with cardiac tamponade in a patient with Down's syndrome. J. Med. Soci. N. J. 68: 101-4, 1971. 

  17. T. Shimamura and A. B. Morrison. Secondary hyperparathyroidism in rats with an experimental chronic renal disease. Exp. Mole. Path. 15: 345-353, 1971.

  18. T. Shimamura. Effects of ureteral obstruction on the structure and function of the renal medulla. Invest. Urol. 9: 484-489, 1972. 

  19. T. Shimamura. Drug-induced medullary necrosis: I. Structural alteration of renal medulla. Arch. Path. 94: 406-410, 1972. 

  20. T. Shimamura and A. B. Morrison. Vascular permeability of the renal medullary vessels in the mouse and rat. Am. J. Path. 71: 155-166, 1973. 

  21. T. Shimamura, M. Aogaichi, and C. Y. Liu. Drug-induced renal medullary necrosis: II. Mode of calcification in the kidney. Exp. Mole. Path. 20: 109-114, 1974. 

  22. T. Shimamura. Drug-induced renal medullary necrosis: III. Increased salt intake and enlargement of the adrenal cortex. Exp. Mole. Path. 22: 176-182, 1975. 

  23. T. Shimamura and A. B. Morrison. A progressive glomerulosclerosis occurring in partial 5/6 nephrectomized rats. Am. J. Path. 79: 95-106, 1975. 

  24. S. Jara and T. Shimamura. Structural alterations of the renal medulla seen in autopsy specimens. Yoko. Med. Bull. 25: 143-54, 1975.

  25. P. W. Washko and R. J. Cousins. Effects of low dietary calcium on chronic cadmium toxicity in rats. Nutri. Rep. Inter. II: 113-127, 1975 (Acknowl.). 

  26. M. Dublin and T. Shimamura. An ultrastructural study of the renal medulla in acute experimental pyelonephritis. Yale J. Biol. Med. 48: 211-16, 1975. 

  27. T. Shimamura and K. Bonk. Repair of the injured papillary tissue in rats. Invest. Urol. 14: 111-114, 1976. 

  28. T. Shimamura and Trojanoski.  Effects of repeated deprivation of drinking water on the structure of renal medulla of rats. Am. J. Path. 84: 87-92, 1976. 

  29. T. Shimamura. Drug-induced renal medullary necrosis: IV. Effects on the urinary Na-output and systemic blood pressure. Exp. Mole. Path. 25: 1-8, 1976. 

  30. M. Sullivan, R. Harvey, and T. Shimamura. The effects of cobra venom factor, an inhibitor of the complement system, on the sequence of morphologic events in the kidney in experimental pyelonephritis. Yale J. Biol. Med. 50: 267-273, 1977. 

  31. T. Shimamura, J. Cotton, and J. C. W. Wang. Site of bacterial colonization in acute pyelonephritis induced in rats by Escherichia coli. Exp. Mole. Path. 29: 253-259, 1978. 

  32. T. Shimamura. Effects of inflammatory mediators on the glomerular localization of intravenously administered ferritins. Experientia 34: 1196-7, 1978. 

  33. T. Shimamura, K. Hayase, J. C. W. Wang, and J. Cotton. Structural alterations of the liver due to administration of N-N'diacetylbenzidine. A new model of cirrhosis. Arch. Path. 103: 327-330, 1979.  

  34. T. Shimamura, V. Savoca, and J. Cotton. Comparative studies of cellular reactions to injuries between the inner medulla and the cortex of rat kidneys. Am. J. Path. 96: 143-148, 1979.

  35. F. E. Cuppage, T. Shimamura, and M. D. McGavin. Nephron obstruction in mutant southdown sheep. Vet. Path. 16: 483-485, 1979. 

  36. T. Shimamura. Mechanisms of renal tissue destruction in an experimental acute pyelonephritis. Exp. Mole. Path. 34: 34-42, 1981. 

  37. T. Shimamura. Relationship of dietary intake to the development of glomerulosclerosis in obese Zucker rats. Exp. Mole. Path. 36: 423-434, 1982. 

  38.  T. Shimamura. Focal glomerulosclerosis in obese Zucker rats and prevention of its development. Kidney Int. Suppl. Vol. 24: S259-S262, 1983.   

  39. T. Shimamura and J. K. Maesaka. A method to identify single microinjected nephrons of rat. Stain Technol. 59(3): 221-224, 1984. 

  40. T. Shimamura and J. K. Maesaka. Phagocytosis of E. coli by renal tubular epithelia. Yale J. Biol. Med. 57: 817-824, 1984. 

  41. L. Weiss, M. Lee, and T. Shimamura. Twin and triplet glomeruli. Am. J. Kid. Dis. 8: 280, 1986. 

  42. T. Shimamura. Growth promotion of urothelial cells by  a silk suture in the bladder walls of rats. Acta Path. Jpn. 37: 273-280, 1987. 

  43. T. Shimamura. Growth promotion by silk sutures in the urinary bladder of rat. Exp. Mole. Path. 47: 262-270, 1987. 

  44. T. Shimamura. Mechanisms of progression of experimental focal segmental glomerulosclerosis. Jpn. J. Nephr. 29: 23, 1987. 

  45. T. Shimamura and G. Strauss. Reaction to vesical foreign bodies in two strains of rats. Jpn. J. Exp. Med. 58: 9-13, 1988.

  46. S. Takahashi and T. Shimamura. A review of factors modulating experimental glomerulosclerosis. Nihon U. Med. Bull. 30: 101-108, 1988. 

  47. T. Shimamura and K. Okada. Chelation of intestinal phosphate absorption and experimental glomerulosclerosis. Jpn. J. Exp. Med. 58: 163-7, 1988. 

  48. T. Shimamura. 11-Deoxycorticosterone-induced hypertension, glomerulosclerosis, and renal arterial and arteriolar lesions. Jpn. J. Exp. Med. 58: 225-8, 1988. 

  49. T. Takahashi, K. Okada, L. Lelkes, and T. Shimamura. Experimental urolithiasis in the bladder of rats. Jpn. J. Exp. Med. 58: 269-272, 1988.     

  50. K. Okada and T. Shimamura. A cilium in the human mesangial cell. Letter, Acta Path. Jpn. 38: 1485-7, 1988(Letter). 

  51. R. A. Karmali, A. Donner, S. Gobel, and T. Shimamura. I. Effect of n-3 and n-6 fatty acids on 7,12 dimethylbenz(a) anthracene-induced mammary tumorigenesis. Anticancer Res. 9: 1161-1168, 1989. 

  52. J. W. Culberson, M. Tang, C. E. Lau, and J. L. Falk. Diazepan and discriminative motor control: acute, chronic and withdrawal effects. Pharma. Biochem. Behav. 35: 419-27, 1990 (Acknowledgement).

  53. T. Shimamura. Prevention of 11-deoxycorticosterone(DOC)-salt induced glomerular hypertrophy and glomerulosclerosis by dietary phosphate binder. Am. J. Path. 136: 549-56, 1990. 

  54. T. Shimamura, L. F. Amorosa, A. C. Wilson, L. Lelkes, and A. Khachadurian. Atherosclerosis and glomerulosclerosis in WHHL and obese Zucker rats. Jpn. J. Exp. Med. 60: 105-9, 1990. 

  55. A. K. Khachadurian, E. Coly, A. AlHinai, C. Martucci, S. H. Schneider, and L. F. Amorosa. Pravastatin decreases serum lipids and vascular cholesterol deposition in Watanabe heritable hyperlipidemic (WHHL) rabbits. Jpn. Heart J. 32: 675-685, 1991. 

  56. T. Shimamura and A.C. Wilson. Influence of dietary fish oil on the aortic, myocardial, and renal lesions of SHR. J. Nutr. Sci. Vitaminol. 37: 581-90, 1991. 

  57. T. Shimamura. L. S. Weiss, J. A. Walker, R. A. Sherman, and R. P. Eisinger. Light nephropathy in a 19-month old boy with AIDS. Acta Path. Jpn. 42: 500-3, 1992. 

  58. T. Shimamura, E. Zycband, A. Covit, and R. P. Eisinger.  Single detached glomerulus in needle biopsy tissue for electron-microscoppy. Acta Path. Jpn. 42: 852-3, 1992 (Letter) 

  59. L. F. Amorosa, S. J. Rozowski, R. Ananthakrishnan, E. Coly, A. AlHinai, C. Martucci, S. H. Schneider, TY. Shimamura, and A. K. Khachadurian. Effects of pravastatin on cholesterol metabolism in Watanabe heritable hyperlipidemic rabbits. Jpn. Heart J. 33: 451-63, 1992. 

  60. K. Okada, S. Takahashi, Y. Nagura, M. Hatano, and T. Shimamura.  Early morphological changes of tubules in rats with chronic renal failure. Nippon Ginzo Gakkai Shi (Jpn. J. Nephr.) 34: 65-70, 1992. 

  61. S. Takahashi, K. Okada, and T. Shimamura. Influence of factors in the digestive tract on the progression of chronic renal failure. Jpn. J. Nephr. 35: 1-11, 1993.

  62.  T. Shimamura and S. Takahashi. Reduced proliferation of cultured bladder cancer cells by indomethacin. N. J. Med. 91: 532-4, 1994.  

  63. M. Duncan, T. Shimamura, and K. Chada. The expression of the helix-loop-helix protein, id, during branching morphogenesis in the kidney. Kidney Int. 46: 324-332, 1994.

  64. T. Shimamura and S. Takahashi. Indomethacin inhibits growth of cultured rat bladder cancer cells, R4909, but not of the transplants. Yoko. Med. Bull. 45: 63-68, 1994. 

  65. T. Shimamura, G. S. LaFavour, and R. P. Eisinger. Coexistence of focal segmental glomerulosclerosis and diabetic glomerulopathy. Path. Int. 45: 257-8, 1995.

  66. T. Shimamura and J. Walker. A collapsing form of glomerulopathy. Path. Int. 45: 520-3, 1995. 

  67. T. Shimamura and L. S. Weiss.  Hypoplastic tubules occurring in diffuse mesangial sclerosis. Path. Int. 46: 904-6, 1996.

  68. J. K. Maesaka, T. Palaia, S. A. Chowdhury, T. Shimamura, S. Fishbane, W. Reichman, A. Coyne, and M. E. El-Sabban. Partial characterization of apoptotic plasma factor in Alzheimer's Disease. Am. J. Physiol. 276: F521-F527, 1999.

  69. T. Shimamura. Renal papilla and maladies of the kidney. The Kidney (Jinzo) 23: 27-32, 2000.
Updated Date
07/18/2007

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