Loren W. Runnels
Assistant Professor
Department of Pharmacology
UMDNJ-Robert Wood Johnson Medical School
Publications:
| Runnels, L.W., Yue, L., and D.E. Clapham. 2002. "The TRPM7 channel is inactivated by PIP2 hydrolysis." Nature Cell Biology. 4(5):329-36. | |
| Clapham, D.E., Runnels, L.W., and C. Strubing. 2001. "The TRP Ion Channel Family." Nature Review Neuroscience. 2(6):387-96. | |
| Runnels, L.W., Yue, L., and D.E. Clapham. 2001. "TRP-PLIK, a bifunctional protein with Kinase and Ion Channel Activities". Science. 291(5506): 1043-1047. | |
| Runnels, L.W. and S.F. Scarlata. 1999. "Determination of the affinities between heterotrimeric G protein subunits and their phospholipase C-beta effectors." Biochemistry. 38(5): 1488-96. | |
| Runnels, L.W. and S.F. Scarlata. 1998. "Regulation of the Rate and Extent of Phospholipase C beta-2 Effector Activation by the beta-gamma Subunits of Heterotrimeric G Proteins." Biochemistry. 37(44):15563-15574. | |
| Tall, E., Dormán, G., Garcia, P., Runnels, L., Shah, S., Chen, J. , Profit, A., Gu, Q., Chaudhary, A., Prestwich, G.D. and M.J. Rebecchi. 1997. "Phosphoinositide-binding Specificity among Phospholipase C Isozymes as Determined by Photocrosslinking to Novel Substrate and Product Analogs." Biochemistry. 36(23):7239-7248 | |
| Runnels, L.W., Jenco, J., Morris, A. and S. Scarlata. 1996. "Membrane Binding of Phospholipases C-b1 and C-b2 Is Independent of Phosphatidylinositol 4,5-Bisphosphate and the alpha and beta-gamma Subunits of G Proteins." Biochemistry. 35(51): 16824-16832. | |
| Glaser, M., Wanaski, S., Buser, C.A., Boguslavsky, V., Rashidzada, W., Morris, A., Rebecchi, M., Scarlata, S.F., Runnels, L.W., Prestwich, G.D., Chen, J., Aderem, A., Ahn, J. and S. McLaughlin. 1996. "Myristoylated Alanine-rich C Kinase Substrate (MARCKS) Produces Reversible Inhibition of Phospholipase C by Sequestering Phosphatidylinositol 4,5-Bisphosphate in Lateral Domains." J Biol Chem 271(42): 26187-26193. | |
| Runnels, L.W. and S.F. Scarlata. 1995 "Theory and Application of Fluorescence Homotransfer to Melittin Oligomerization" Biophysical Journal. 69: 1569-1583. |
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