Brett E. Lewis , M.D., Ph.D.

Chief Resident Physician Tel:   732-253-3939 Email:lewisbr@umdnj.edu

Education:

• B.S in physics              University of Florida, Gainesville, FL         
• M.D.                             Albert Einstein College of Medicine, NY
• Ph.D.                           Albert Einstein College of Medicine,NY
• Residency                   Robert Wood Johnson Medical School - UMDNJ

Honors:

• Dean's Recognition Award 2004, Albert Einstein College of Medicine, 2004
• Julius Marmur Research Award, 2002, Albert Einstein College of Medicine
• Rudin Scholar 2001-2002, Albert Einstein College of Medicine
• Phi Beta Kappa, inducted 1993, Beta Chapter of Florida

Academic Appointment:

• Resident Physician

Selected Peer-Reviewed Publications for the recent 5 years:

1. Brett E. Lewis, Nankishoresing Choytun, Vern L. Schramm, and Andrew Bennet, Transition States for Glucopyranose Interconversion, Journal of the American Chemical Society 2006, 128: 5049-5058.
2. Brett E. Lewis and Vern L. Schramm, Enzymatic Binding Isotope Effects and the Interaction of Glucose with Hexokinase, In Insotopes in Chemistry and Biology, Kohen, A. and Limbach, H.-H. eds, CRC Press, Boca Raton, FL., pp. 1019-1053, 2006.
3. Brett E. Lewis and Vern L. Schramm, Isotope Effect-Mapping of the Ionization of Glucose Demonstrates Unusual Charge Sharing, Journal of the American Chemical Society 2003, 125: 7872-7877.
4. Brett E. Lewis and Vern L. Schramm, Binding Equilibrium Isotope Effects for Glucose at the Catalytic Domain of Human Brain Hexokinase, Journal of the American Chemical Society 2003, 125: 4785-4798.
5. Brett E. Lewis and Vern L. Schramm, Glucose Binding Iostope Effects in the Ternary Complex of Brain Hexokinase Demonstrate Partial Relief of Ground-State Destabilization, Journal of the American Chemical Society 2003, 125: 4672-4673.
6. Brett E. Lewis and Vern L. Schramm, Fine Print in Isotope Effects: The Glucose Anometric Equilibrium and Binding of Glucose to Human Brain Hexokinase, Nukleonika 2002, 47: S3-S7.
7. Brett E. Lewis and Vern L. Schramm, Conformational Equilibrium Isotope Effects in Gluocose by 13-C NMR Spectroscopy and Computational Studies, Journal of the American Chemical Society, 2001,123:1327-1336.

Presentations at Scientific Meetings:

1. Isotope Effects in Conformational and Binding Equilibria. Glucose and Human Brain Hexokinase.  Julius Marmur Award Research Symposium, Oral Presentation, March 2002
2. Brett E. Lewis and Vern L. Schramm, Glucose and Human Brain Hexokinase: Isotope Effects in Conformational and Binding Equilbria, Gordon Research Conference in Isotopes, January 2002.
3. Brett E. Lewis and Vern L. Schramm, Glucose and Human Brain Hexokinase, Isotope Effects in Conformational and Binding Equilibria, Oral Presentation, MSTP Retreat, Mohonk, NY, September, 2001.
4. Brett E. Lewis and Vern L. Schramm, Isotope Effects in Conformational and Binding Equilibria: Glucose and Human Brain Hexokinase, 17th Enzyme Mechanisms Conference, Janurary 2001.
5. Brett E. Lewis and Vern L. Schramm, Isotope Effects on Anomeric Equilibrium and Binding of Glucose to Brain Hexokinase, Gordon Research Conference in Isotopes, January 2000.
6. Brett E. Lewis and Vern L. Schramm, Isotope Effects on Anomeric Equilibrium and Binding of Glucose to Brain Hexokinase, 16th Enzyme Mechanisms Conference, January 1999.