Recent Submissions

Mercado, M. L. T., Meiners, S., Crockett, D.P., Mathus, T., Yurchenco, P. D. and Geller, H. M. Neuronal guidance by laminin-1 domains, submitted.Click Here for Abstract

Gross, S. R., Hoffmann, B. and Geller, H. M., DNA damage-induced neuronal apoptosis requires JNK-dependent upregulation of cyclin D1, submitted.  Click Here for Abstract

Published Papers

Romero, A. A., Gross, S. R., Cheng, K.-Y., Goldsmith, N. K. and Geller, H. M., An age-related increase resistance to DNA damage-induced apoptotic cell death is associated with development of DNA repair mechanisms, J. Neurochem, 84:1275-87, 2003 . Click Here for Abstract

Geller, H. M., Cheng, K.-Y.,, Goldsmith, N. K., Romero, A. A., Zhang, A., Morris, E. J. and Grandison, L.Oxidative stress mediates DNA damage and neuronal apoptosis in response to cytosine arabinoside, J. Neurochem, 78:265-275, 2001.  Click Here for Abstract

Powell, E. M, Mercado, M. L. T., Calle-Patino, Y. A. and Geller, H. M. Protein kinase C mediates neurite guidance at an astrocyte boundary, Glia, 33:288-297, 2001. Click Here for Abstract

Meiners, S., Mercado, M. L. T. and Geller, H. M. The multi-domain structure of extracellular matrix molecules: implications for nervous system regeneration, Prog. Brain Res., 128:23-31, 2000. Click Here for Abstract

Park, D. S., Morris, E. J., Bremner, R., Keramaris, E., Padmanabhan, J., Rosenbaum, M., Shelanski, M. L., Geller, H. M., and Greene, L. A. Involvement of retinoblastoma family members and E2F/DP1 complexes in death of neurons evoked by DNA damage, J. Neurosci, 20:3104-3114, 2000.  Click Here for Abstract

Fidler, P. S., Schuette, K., Thornton, S. R., Asher, R. A., Dobbertin, A., Thornton, S.  R., Calle-Patino, Y., Muir, E.. Levine, J. M., Geller, H. M., Rogers, J. H. , Faissner, A., and Fawcett, J. W. Comparing astrocytic cell lines that are inhibitory or permissive for axon growth: The major axon-inhibitory proteoglycan is NG2, J. Neurosci., 19:8778-8788, 1999.Click Here for Abstract

Meiners, S., Mercado, M. L. T.,  Nur-e-Kamal, M. S. and Geller, H. M.  Tenascin-C contains domains that independently regulate neurite outgrowth and neurite guidance, J. Neurosci., 19:8443-8453, 1999. Click Here for Abstract

Meiners, S., Powell, E. M. and Geller, H. M Neurite outgrowth promotion by the alternatively spliced region of tenascin-C is influenced by cell-type specific binding, Matrix Biology, 18:75-87, 1999. Click Here for Abstract

Powell, E. M. and Geller, H. M. A dissection of astrocyte-mediated cues in neuronal guidance and process extension, Glia, 26:73-83, 1999. Click Here for Abstract

Morris, E. J., Dreixler, J.V.,  Cheng, Ke-Yi, Wilson, P. M., Gin, R. M and Geller, H. M. An optimization of single cell gel electrophoresis (SCGE) for quantitative analysis of neuronal DNA damage, BioTechniques, 26:282-289, 1999.Click Here for Abstract
Click Here for Macro and Sample Comets

Di Prospero, N. A., Zhou, X.-R., Meiners, S., McAuliffe, W.G., Ho, S.-Y. and Geller, H. M. Suramin disrupts the gliotic response following a stab wound injury to the adult rat brain. J. Neurocytol., 27:491-506, 1998.Click Here for Abstract

Park, D. S., Morris, E. J., Padmanabhan, J., Shelanski, M. L., Geller, H. M., and Greene, L. A.  Cyclin-dependent kinases participate in death of neurons evoked by DNA damaging agents, J.  Cell Biol., 143:457-467, 1998.  Click Here for Abstract

Fawcett, J. W. and Geller, H. M.  Research News: Regeneration in the CNS: optimism mounts.  Trends.  Neurosci., 21:179-180, 1998.Click Here for Abstract

Park, D. S., Morris, E. J., Stefanis, L., Troy, C.M., Shelanski, M.L., Geller, H. M. and Greene, L. A. Multiple pathways of neuronal death induced by DNA-damaging agents. NGF deprivation, and oxidative stress, J. Neurosci., 18:830-840, 1998. Click Here for Abstract

Truckenmiller, M. E., Tornatore, C., Wright, R. D., Dillon-Carter, O., Meiners, S., Geller, H. M., Freed, W. J. A truncated SV40 large T antigen lacking the p53 binding domain overcomes p53-induced growth arrest and immortalizes primary mesencephalic cells. Cell. Tiss. Res., 291:175-189, 1998. Click Here for Abstract

Diprospero, N. A., Meiners, S., and Geller, H. M. Inflammatory cytokines interact to modulate extracellular matrix and astrocytic support of neurite outgrowth. Exptl. Neurol., 148:628-639, 1997. Click Here for Abstract  Click Here for Adobe Acrobat File

Meiners, S. and Geller, H. M. Long and short splice variants of human tenascin differentially regulate neurite outgrowth. Mol. Cell. Neurosci., 10:100-116, 1997. Click Here for Abstract Click Here for Adobe Acrobat File

Powell, E. M., Fawcett, J. W. and Geller, H. M. Neurite guidance by astrocyte proteoglycans. Mol. Cell. Neurosci., 10:27-42, 1997. Click Here for Abstract Click Here for Adobe Acrobat File

Powell, E. M., Meiners, S., Di Prospero, N. A., and Geller, H. M. Mechanisms of astrocyte directed neurite guidance. Cell Tiss. Res., 290:385-393, 1997.Click Here for Abstract

Park, D. S., Morris, E. J., Greene, L. A. and Geller, H. M. G1/S cell cycle blockers and inhibitors of cyclin dependent kinases suppress camptothecin-induced neuronal apoptosis. J. Neurosci., 17:1256-1270, 1997. Click Here for Abstract

Morris, E. J. and Geller, H. M. Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: Evidence for cell-cycle independent toxicity. J. Cell Biol., 134:757-770, 1996. Click Here for Abstract

Zhang, X., Phelan, K. D. and Geller, H. M. A novel tetrodotoxin-resistant sodium current from an immortalized neuroepithelial cell line. J. Physiol., 490:17-29, 1996. Click Here for Abstract

Okoye, G. S. and Geller, H. M. Migration of A7 Immortalized astrocytic cells grafted into the adult rat striatum. J. Comp. Neurol., 362:524-534, 1995. Click Here for Abstract

Marone, M., Quiñones-Jenab, V., Meiners, S., Nowakowski, R. S., Ho, S.-Y. and Geller, H. M. An immortalized mouse hypothalamic cell line with neuronal and glial phenotypes. Dev. Neurosci., 17:311-323, 1995. Click Here for Abstract

Meiners, S., Powell, E. M. and Geller, H. M. A distinct subset of tenascin/CS-6-PG-rich astrocytes restricts neuronal growth in vitro. J. Neurosci., 15:8096-8108, 1995. Click Here for Abstract

Basma, A., Morris, E. J., Nicklas, W. J. and Geller, H. M. L-DOPA toxicity to PC12 cells in culture is via its autoxidation. J. Neurochem., 64:825-832, 1995. Click Here for Abstract

Petroski, R. E. and Geller, H. M. Selective labelling of cultured embryonic neurons on astrocytes with 5(6) carboxyfluorescein diacetate (CFDA). J. Neurosci. Meth., 52:23-30, 1994. Click Here for Abstract

Okoye, G. S., Freed, W. J. and Geller, H. M. Short-term immunosuppression enhances the survival of intracerebral grafts of A7-immortalized glial cells. Exptl. Neurol., 128:191-201, 1994.Click Here for Abstract

Smith-Thomas, L. C., Fok-Seang, J., Stevens, J., Du, J.-S., Muir, E., Faissner, A., Geller, H. M., Rogers, J. H. and Fawcett, J. W. An inhibitor of neurite outgrowth produced by astrocytes. J. Cell Sci., 107:1687-1695, 1994. Click Here for Abstract

Meiners, S., Marone, M., Rittenhouse, J. L. and Geller, H. M. Regulation of astrocytic tenascin by basic fibroblast growth factor. Dev. Biol., 179:480-493, 1993. Click Here for Abstract

Nicklas, W. J., Saporito, M. S., Basma, A., Geller, H. M. and Heikkila, R. E. Mitochondrial mechanisms of neurotoxicity. Ann. N.Y. Acad Sci., 648:28-36, 1992. Click Here for Abstract

Saporito, M. S., Youngster, S. K., Heikkila, R. E., Geller, H. M. and Nicklas, W. J. Dopaminergic neurotoxicity of 1-methyl-4-phenylpyridinium analogs in cultured neurons: relationship of dopamine uptake affinity and inhibition of mitochondrial respiration. J. Pharmacol. Expt'l. Thera., 260:1400-1409, 1992. Click Here for Abstract

Grierson, J. P., Petroski, R. E., O'Connell, S. M. and Geller, H. M. Calcium homeostasis in dissociated embryonic neurons: a flow cytometric analysis. J. Neurophysiol., 67:704-714, 1992. Click Here for Abstract

Basma, A. N., Heikkila, R. E., Saporito, M. S., Geller, H. M. and Nicklas, W. J. 1-methyl-4-(2' ethylphenyl)-1,2,3,6-tetrahydropyridine-induced toxicity in PC12 cells is enhanced by preventing glycolysis. J. Neurochem., 58:1052-1059, 1992. Click Here for Abstract

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